肾结石患者钙和维生素D补充剂的应用一项观察性前瞻性研究

M. Akel, Iqbal M. Fahs
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引用次数: 1

摘要

导读:钙和维生素D补充剂的摄入与肾结石有关,因为大约80%的肾结石含有钙。然而,关于这些补充剂管理的研究产生了相互矛盾的数据。目的:在本研究中,我们旨在评估黎巴嫩患者中钙和维生素D补充剂的摄入量及其与肾结石的显著相关性。患者和方法:研究在黎巴嫩所有地区随机选择的肾科诊所进行,为期3个月。数据分析采用SPSS 22。结果:550名研究对象的平均年龄为42.12±15.59岁,其中男性51.5%,女性48.5%。几乎一半的参与者有肾结石病史(53.8%)。钙和维生素D补充剂的使用率分别为19.6%和18.2%。钙和维生素D补充剂的摄入与肾结石病史无显著相关性(钙:10.4% vs 9.3%, P = 0.446;维生素D: 9.1%对9.1%,P = 0.231)。结论:本研究显示,肾结石患者补充钙和维生素D的摄入量与肾结石病史无显著相关性。这些患者,特别是那些服用钙补充剂的患者,应定期监测他们的钙水平,以避免高钙尿症和随之而来的结石形成。
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Calcium and vitamin D supplements administration in patients with nephrolithiasis; an observational prospective study
Introduction: Calcium and vitamin D supplements intake have been linked to nephrolithiasis as around 80% of kidney stones contain calcium. However, studies regarding these supplements administration yielded conflicting data. Objectives: In this study we aimed to assess calcium and vitamin D supplements intake and the presence of significant association with nephrolithiasis among Lebanese patients. Patients and Methods: The study was conducted at nephrology clinics selected randomly from all Lebanese districts over a 3-month period. Data analysis was conducted with SPSS version 22. Results: The mean age of the 550 studied participants was 42.12±15.59 years with 51.5% males and 48.5% females. Almost half of the participants had a history of kidney stones (53.8%). Calcium and vitamin D supplements were utilized by 19.6% and 18.2%, respectively. Calcium and vitamin D supplements intake were not associated significantly with history of kidney stones (calcium: 10.4% versus 9.3%, P = 0.446; vitamin D: 9.1% versus 9.1%, P = 0.231). Conclusion: This study revealed that supplemental calcium and vitamin D intake among nephrolithiasis patients had no significant associations with history of kidney stones. Those patients, especially those taking calcium supplements should be counseled to monitor regularly their calcium levels to avoid hypercalciuria and consequent stone formation.
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