{"title":"具体的物质遭遇和生物医学未来的模糊承诺:生物衍生药物的案例","authors":"Mianna Meskus, Venla Oikkonen","doi":"10.1080/14636778.2020.1778459","DOIUrl":null,"url":null,"abstract":"Therapies and prophylactics using biologically derived materials such as cells, microbes or tissues are often portrayed as key to increased future health. This article investigates the material preconditions of such visions. Building on feminist new materialist approaches, it explores the embodied material encounters between biologicals administered into living bodies and the vibrant materiality of the body. We investigate embodied material encounters through two biologicals, pandemic vaccines and stem cell therapies, focusing on vaccine-associated narcolepsy during the 2009 pandemic, and adverse reactions in an experimental stem cell therapy targeting an eye disease called AMD. We propose that the concept of embodied material encounter provides an important tool for STS by making visible the constitutive situatedness of risk and promise and the multiplicity of futures in therapeutically harnessed biological processes. We argue that ethically accountable visions of biomedical futures need to be anchored in a nuanced understanding of these embodied processes.","PeriodicalId":54724,"journal":{"name":"New Genetics and Society","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2020-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Embodied material encounters and the ambiguous promise of biomedical futures: The case of biologically derived medicines\",\"authors\":\"Mianna Meskus, Venla Oikkonen\",\"doi\":\"10.1080/14636778.2020.1778459\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Therapies and prophylactics using biologically derived materials such as cells, microbes or tissues are often portrayed as key to increased future health. This article investigates the material preconditions of such visions. Building on feminist new materialist approaches, it explores the embodied material encounters between biologicals administered into living bodies and the vibrant materiality of the body. We investigate embodied material encounters through two biologicals, pandemic vaccines and stem cell therapies, focusing on vaccine-associated narcolepsy during the 2009 pandemic, and adverse reactions in an experimental stem cell therapy targeting an eye disease called AMD. We propose that the concept of embodied material encounter provides an important tool for STS by making visible the constitutive situatedness of risk and promise and the multiplicity of futures in therapeutically harnessed biological processes. We argue that ethically accountable visions of biomedical futures need to be anchored in a nuanced understanding of these embodied processes.\",\"PeriodicalId\":54724,\"journal\":{\"name\":\"New Genetics and Society\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2020-06-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"New Genetics and Society\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/14636778.2020.1778459\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"New Genetics and Society","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/14636778.2020.1778459","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
Embodied material encounters and the ambiguous promise of biomedical futures: The case of biologically derived medicines
Therapies and prophylactics using biologically derived materials such as cells, microbes or tissues are often portrayed as key to increased future health. This article investigates the material preconditions of such visions. Building on feminist new materialist approaches, it explores the embodied material encounters between biologicals administered into living bodies and the vibrant materiality of the body. We investigate embodied material encounters through two biologicals, pandemic vaccines and stem cell therapies, focusing on vaccine-associated narcolepsy during the 2009 pandemic, and adverse reactions in an experimental stem cell therapy targeting an eye disease called AMD. We propose that the concept of embodied material encounter provides an important tool for STS by making visible the constitutive situatedness of risk and promise and the multiplicity of futures in therapeutically harnessed biological processes. We argue that ethically accountable visions of biomedical futures need to be anchored in a nuanced understanding of these embodied processes.
期刊介绍:
New Genetics and Society: Critical Studies of Contemporary Biosciences is a world-leading journal which:
-Provides a focus for interdisciplinary and multi-disciplinary, leading-edge social science research on the new genetics and related biosciences;
-Publishes theoretical and empirical contributions reflecting its multi-faceted development;
-Provides an international platform for critical reflection and debate;
-Is an invaluable research resource for the many related professions, including health, medicine and the law, wishing to keep abreast of fast changing developments in contemporary biosciences.
New Genetics and Society publishes papers on the social aspects of the new genetics (widely defined), including gene editing, genomics, proteomics, epigenetics and systems biology; and the rapidly developing biosciences such as biomedical and reproductive therapies and technologies, xenotransplantation, stem cell research and neuroscience. Our focus is on developing a better understanding of the social, legal, ethical and policy aspects, including their local and global management and organisation.