调强放射治疗(IMRT)的动态体绘制

Rajarathinam Arangarasan, Sungeun Kim, S. Orçun
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引用次数: 0

摘要

几十年来,放射疗法在癌症治疗中被证明是成功的。放射治疗的主要任务是对肿瘤细胞施加最大剂量的辐射。IMRT技术通过将加速器头分成可以独立操作的更小的“束”单元,使更精确地传递辐射成为可能。这种治疗计划需要医生和IMRT技术人员之间耗时的反复工作。目前最先进的技术是在开始时确定IMRT治疗计划,并在治疗过程中不改变它。然而,在整个IMRT治疗过程中,假设固定的“靶体积”是非常有限的,因为肿瘤在放射治疗后会缩小。在本研究中,我们将时变体积绘制技术应用于IMRT治疗,并开发了一个概念验证原型系统,该系统能够捕获和关联整个治疗过程中辐照体积的时间依赖性变化。这个原型系统将使研究人员能够探索不同的假设情景,例如根据放射剂量确定“目标治疗量”。
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Dynamic Volume Rendering for Intensity Modulated Radiation Therapy (IMRT) Treatment
For some decades, radiation therapy has been proved successful in cancer treatment. The major task of radiation therapy is to impose a maximum dose of radiation to the tumor cells. The IMRT technology makes it possible to deliver radiation more precisely by dividing the accelerator head into smaller units called “beamlets” that can be manipulated independently. This treatment planning requires a time consuming iterative work between a physician and an IMRT technician. The state of the art current technique is to determine the IMRT treatment plan at the beginning and use it without changing it in the course of the treatment. However, the assumption of fixed ‘target volume’ throughout the IMRT treatment, is very limiting given that the tumor shrinks in response to the radiation therapy. In this research, we apply time-varying volume rendering technique to the IMRT treatment and develop a proof-of-concept prototype system that enables capturing and relating the time dependent changes of the irradiated volume throughout the course of treatment. This prototype system will enable the researchers to explore different what-if scenarios, such as determining the ‘Target Treatment Volume’ depending on the delivered dose of radiation.
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