组织扩张器用于儿童头皮重建并发地曲霉真菌感染。

Eplasty Pub Date : 2023-01-01
Shelley R Edwards, Katherine C Benedict, John Sullivan, Roberto Santos, Ian Hoppe
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引用次数: 0

摘要

背景:组织扩张是儿童头皮软组织重建的有效选择。不幸的是,这种方法有很高的并发症风险,如感染和扩张器暴露。虽然同种异体材料的细菌感染是最常见的,但当真菌感染发生时,结果可能是毁灭性的。目的:为了解真菌组织扩张器感染的处理方法,本报告描述了一例以扩张器为基础的头皮重建并发地曲霉感染的儿科患者。方法:1例钝力颅脑外伤患者以软组织损伤和凹陷性颅骨骨折为主要表现,需要紧急开颅手术。稳定后,由于软组织覆盖不足,需要在重建颅骨成形术前进行进一步的手术干预。在她受伤六个月后,放置了两个远端半裂片下组织扩张器。随后,手术切口出现脓性引流。结果:感染导致扩张器暴露,需要取出扩张器并给予克林霉素和头孢他啶治疗,同时等待培养结果。术中培养为地曲霉和甲氧西林敏感金黄色葡萄球菌阳性,患者全身接受伏立康唑治疗23天,头孢氨苄治疗10天。结论:虽然组织扩张仍然是一种可行的重建选择,但真菌感染可能是灾难性的,需要全身抗真菌治疗、手术清创和取出扩张器。
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Tissue Expander for Pediatric Scalp Reconstruction Complicated by Fungal Infection With Aspergillus terreus.

Background: Tissue expansion is an effective option for soft tissue reconstruction of the scalp in the pediatric population. Unfortunately, this approach carries a high risk of such complications as infection and expander exposure. While bacterial infection of alloplastic materials is most frequent, when fungal infections occur, the outcomes can be devastating.

Purpose: To inform the management of fungal tissue expander infections, this report describes a case of expander-based scalp reconstruction complicated by Aspergillus terreus infection in a pediatric patient.

Methods: A patient who had blunt-force head trauma presented with soft tissue injury and depressed skull fracture requiring emergent craniectomy. After stabilization, a paucity of soft tissue coverage required further surgical intervention before reconstructive cranioplasty. Six months after her injury, two remote port subgaleal tissue expanders were placed. Subsequently, purulent drainage developed from the surgical incision.

Results: Infection resulted in expander exposure requiring device removal and treatment with clindamycin and ceftazidime while awaiting culture results. Intraoperative cultures were positive for Aspergillus terreus and methicillin-sensitive Staphylococcus aureus, for which she received systemic voriconazole for 23 days and cephalexin for 10 days.

Conclusions: Though tissue expansion remains a viable reconstructive option, fungal infection can be disastrous, requiring systemic antifungal therapy, surgical debridement, and expander removal.

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