西班牙初级卫生保健抗高血压药物使用趋势(1990- 2012年)

M. Cáceres, P. Moyano, H. Fariñas, J. Cobaleda, A. Pijierro, P. Dorado, A. Llerena
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引用次数: 16

摘要

目的:本研究旨在描述1990年至2012年埃斯特雷马杜拉(西班牙)抗高血压药物的使用情况及其经济影响。方法:从西班牙埃斯特雷马杜拉市卫生系统报销的社区药房销售数据中获取降压药(atcco2、C03、C07、C08、C09)的使用情况。数据以限定日剂量(DDD)和每1000居民每日DDD (DHD)表示。结果:埃斯特雷马杜拉的降压药消费量从1990年的67.1 DHD增加到2012年的315.2 DHD(增加3.7倍)。作用于肾素-血管紧张素系统(C09)的药物占总增加的75%。自2007年以来,血管紧张素II拮抗剂的使用比ACE抑制剂增加。结论:近23年来,埃斯特雷马杜拉市降压药用量显著增加。在过去的几年里,血管紧张素II拮抗剂药物的使用产生了重大的经济影响。
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Trends in Antihypertensive Drug Use in Spanish Primary Health Care (1990- 2012)
Objective: This study aimed to describe the use of antihypertensive in Extremadura (Spain) from 1990 to 2012 and its economic impact. Method: Information on antihypertensive drug (ATC C02, C03, C07, C08, C09) utilization was obtained from the community pharmacy sales figures reimbursed by the Health System of Extremadura (Spain). Data were expressed in Defined Daily Dose (DDD) and DDD per 1000 inhabitants per day (DHD). Results: Antihypertensive consumption in Extremadura increased from 67.1 DHD in 1990 to 315.2 in 2012 (an increase of 3.7 times). Agents acting on the Renin-Angiotensin System (C09) are responsible for 75% of the total increase. Since 2007 the use of Angiotensin II antagonist increased over ACE inhibitors. Conclusions: The consumption of antihypertensive drugs in Extremadura increased remarkably in the last 23 years. In the last years the use of angiotensin II antagonist drugs is having a significant economic impact.
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