预防性地塞米松或哌替啶预防脊髓麻醉下经尿道前列腺切除术术后寒战

Abd-Elazeem El Bakry, E. Ibrahim
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引用次数: 10

摘要

背景:寒战是脊柱麻醉下老年泌尿外科手术患者的常见并发症。本研究比较了脊髓麻醉下预防性地塞米松和哌替啶对经尿道前列腺切除术(TURP)中寒战的影响。患者与方法本随机前瞻性双盲对照研究对90例脊柱麻醉下行TURP手术的患者进行研究。将患者分为三组:C组患者在脊髓麻醉前静脉注射生理盐水10 ml。P组给予哌替啶25 mg,加入生理盐水10 ml。D组患者给予0.1 mg/kg地塞米松,加入生理盐水10 ml。记录核心体温、平均动脉血压、呼吸频率、血氧饱和度、寒战、恶心、呕吐和瘙痒的发生率和严重程度。结果哌替啶组和地塞米松组寒战发生率和严重程度均低于对照组(P < 0.05),哌替啶组和地塞米松组间差异无统计学意义(P > 0.05)。结论预防性地塞米松与哌啶可有效降低脊柱麻醉下TURP患者寒战的发生率和严重程度。
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Prophylactic dexamethasone or pethidine for the prevention of postoperative shivering during transurethral resection of the prostate under spinal anesthesia
Background Shivering is a common complication in elderly patients undergoing urologic operations under spinal anesthesia. The present study compares the effect of prophylactic dexamethasone and pethidine on shivering during transurethral resection of the prostate (TURP) under spinal anesthesia. Patients and methods This random prospective double-blinded controlled study was conducted on 90 patients scheduled for TURP operations under spinal anesthesia. Patients were allocated into three groups: in the C group, patients were administered intravenous 10 ml normal saline before spinal anesthesia. In the P group, patients were administered 25 mg pethidine in 10 ml normal saline. In the D group, patients were administered 0.1 mg/kg dexamethasone in 10 ml normal saline. Core body temperature, mean arterial blood pressure, respiratory rate, oxygen saturation, incidence and severity of shivering, nausea, vomiting, and pruritus were recorded. Results The incidence and severity of shivering were low in the pethidine and dexamethasone groups compared with the control group (P < 0.05), with no significant difference between the pethidine and dexamethasone groups (P > 0.05). Conclusion Prophylactic dexamethasone is as effective as pethidine in reducing the incidence and severity of shivering in TURP patients under spinal anesthesia.
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