植物介导的纳米金绿色合成及其抗癌应用综述

Senthil Kumar Raju, Praveen Sekar, S. Kumar, Maruthamuthu Murugesan, M. Karthikeyan
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引用次数: 0

摘要

金纳米粒子具有多种物理、化学、光学和机械性能,在医学领域有着广泛的应用,是纳米技术中最有前途的药剂。近年来,纳米金的绿色合成因其广泛的应用和低毒性而引起了研究人员的兴趣。由于存在酚类化合物、黄酮类化合物、生物碱、萜类化合物、多酚类化合物、多糖等植物成分,利用植物介导的提取物合成金纳米颗粒的还原速度最快。蛋白质、维生素和矿物质都包含在提取物中,作为稳定剂和封盖剂。金纳米颗粒是由植物提取物制成的,是天然来源,它们被认为对生物医学用途更安全。本文就植物介导的金纳米颗粒生物合成及其在癌症治疗中的应用作一综述。
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PLANT-MEDIATED GREEN SYNTHESIS OF GOLD NANOPARTICLES AND THEIR ANTICANCER APPLICATIONS: AN UPDATED REVIEW
Due to the wide range of applications in the field of medicine, gold nanoparticles are the most promising agents in nanotechnology with a variety of physical, chemical, optical and mechanical properties. Researchers have been interested in the green synthesis of gold nanoparticles in recent years because of their wide range of applications and low toxicity. The synthesis of gold nanoparticles using plant-mediated extracts has shown the fastest reduction due to the presence of phytoconstituents like phenolic compounds, flavonoids, alkaloids, terpenoids, polyphenols, polysaccharides, etc. Proteins, vitamins and minerals are included in the extracts and act as stabilizing and capping agents. Gold nanoparticles are made from plant extracts and are of natural origin, they are thought to be safer for biomedical uses. In this review, we elaborate about the plant mediated biosynthesis of gold nanoparticles and its biological applications with special emphasize to cancer therapeutics.
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