COVID-19大流行与大流行前时期:常见神经系统疾病的住院率、住院时间和住院死亡率的变化

Alessandra R. De Leon, C. Go
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摘要

背景与目的:COVID-19大流行导致该国卫生保健系统进行了大规模调整。本研究确定了在COVID-19大流行期间和大流行前期间常见(与covid无关)神经系统疾病的住院率、住院时间和住院死亡率的变化。方法:本研究对2019年3月至2020年3月(大流行前组)和2020年4月至2021年4月(COVID-19大流行组)何塞·雷耶斯纪念医疗中心神经内科收治的患者进行了回顾性横断面研究。计算脑血管疾病、中枢神经系统感染、中枢神经系统肿瘤和癫痫性疾病的住院率、住院时间和住院死亡率。结果:2019年4月至2020年3月招收1090人,2020年4月至2021年3月招收393人,总体下降63%。大流行期间,中枢神经系统肿瘤的住院时间更长。脑血管疾病、中枢神经系统感染和癫痫发作的住院时间差异无统计学意义。住院总死亡率由22.75%上升至26.46%,脑血管病病死率显著上升。结论:我们观察到总体住院率和住院时间的大幅下降。在大流行期间,总体住院死亡率也有所上升。
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COVID-19 Pandemic vs. Pre-Pandemic Period: Changes in Hospital Admission Rates, Length of Stay, and In-Hospital Mortality of Common Neurologic Conditions
Background and Objective: COVID-19 pandemic caused massive adjustments to healthcare systems in the country. This study determined the change in hospital admission rates, length of hospital stay and in-hospital mortality of common (non-COVID related) neurologic conditions during the COVID-19 pandemic and pre-pandemic period. Methods: The study utilized a retrospective cross-sectional study of patients admitted under the Department of Neurology at Jose R. Reyes Memorial Medical Center from the period of March 2019 to March 2020 (pre-pandemic group), and April 2020 to April 2021 (COVID-19 pandemic). Admission rates, length of stay and in-hospital mortality were calculated for cerebrovascular diseases, CNS infections, CNS neoplasms and Seizure disorders. Results: There were 1090 admissions from April 2019 to March 2020 and 393 admissions from April 2020 to March 2021 with an over-all decline of 63%. During the pandemic, the duration of hospital stay was longer for CNS neoplasms. Duration of hospital stay for cerebrovascular disease, CNS infection, and seizure disorders were not significantly different. There was an increase in over-all in hospital mortality from 22.75% to 26.46% with significant increase in the case fatality rate of cerebrovascular diseases. Conclusion: We observed a large decline in the over-all admission rate and longer hospital stays. The over-all in-hospital mortality rate also increased during the pandemic period.
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