"我更喜欢在计划发生性行为时服药":乌干达坎帕拉青少年对按需口服与每日口服接触前预防的看法。

IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Ajar-African Journal of Aids Research Pub Date : 2022-03-01 DOI:10.2989/16085906.2022.2039727
Rachel Kawuma, Zam Nabalwanyi, Janet Seeley, Yunia Mayanja
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引用次数: 0

摘要

在撒哈拉以南非洲地区的青少年中,有关按需和每日暴露前预防疗法(PrEP)使用情况的信息非常有限。我们采用定性数据收集方法,探讨了乌干达坎帕拉 14 至 19 岁的艾滋病感染高危人群对这两种疗法的看法。数据按主题进行分析,并根据可接受性框架中的结构进行解释。虽然在对特定治疗方案的偏好上没有明显的性别差异,但 PrEP 的可接受性取决于研究时 AYP 的个人性行为。那些认为自己感染艾滋病毒的风险较高的人更倾向于使用每日服药的 PrEP,理由是每日服药具有连贯性,而且他们认为这种方法既有效又安全。性生活不太频繁的青壮年则更喜欢按需 PrEP,因为这可以让他们 "为性生活做好计划"。然而,这两个群体都认为每天服用 PrEP 是一种负担,这阻碍了他们接受这种形式的 PrEP。AYP 预计,每天服药会给他们带来很大压力,需要付出很多努力,而且会打乱他们的日常工作。因此,虽然按需和每日服用 PrEP 都能被这些青少年接受并从中受益,但对这两种方案的偏好取决于自我感觉的风险。因此,口服 PrEP 的使用应根据最终用户的偏好和风险状况进行调整。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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"I prefer to take pills when I plan to have sex": Perceptions of on-demand versus daily oral pre-exposure prophylaxis among adolescents in Kampala, Uganda.

There is limited information about the use of on-demand and daily pre-exposure prophylaxis (PrEP) among adolescents and young people (AYP) in sub-Saharan Africa. We explored perceptions of both regimens among 14- to 19-year-olds perceived to be at high risk of HIV infection in Kampala, Uganda, using qualitative data collection methods. Data were analysed by theme and interpreted based on constructs from the framework of acceptability. Although there were no noticeable gender differences in preferences for a particular regimen, acceptability of PrEP depended on individual AYP sexual behaviour at the time of the study. Those who perceived themselves to be at increased risk of acquiring HIV preferred using daily PrEP, citing the consistency that comes from taking a pill daily and which they considered to be efficacious and safe. AYP who had less frequent sex preferred on-demand PrEP because it would enable them to "plan for sex". However, both groups perceived taking daily PrEP to be a burden, which was an impediment to acceptance of this form of PrEP. AYP anticipated that daily pill taking would be very stressful, requiring a lot of effort and would interrupt their daily routine. Therefore, while both on-demand and daily PrEP were acceptable and beneficial to these AYP, preferences for either regimen depended on self-perceived risk. Thus, oral PrEP use should be tailored to end-user preferences and risk profiles.

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来源期刊
Ajar-African Journal of Aids Research
Ajar-African Journal of Aids Research 医学-公共卫生、环境卫生与职业卫生
CiteScore
1.80
自引率
8.30%
发文量
38
审稿时长
>12 weeks
期刊介绍: African Journal of AIDS Research (AJAR) is a peer-reviewed research journal publishing papers that make an original contribution to the understanding of social dimensions of HIV/AIDS in African contexts. AJAR includes articles from, amongst others, the disciplines of sociology, demography, epidemiology, social geography, economics, psychology, anthropology, philosophy, health communication, media, cultural studies, public health, education, nursing science and social work. Papers relating to impact, care, prevention and social planning, as well as articles covering social theory and the history and politics of HIV/AIDS, will be considered for publication.
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