互联网提供的基于家庭的认知行为疗法对自闭症青年焦虑和强迫症的开发和试点测试

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-04-01 DOI:10.1016/j.jocrd.2023.100789
Andrew G. Guzick , Sophie C. Schneider , Amanda B. Perozo Garcia , Minjee Kook , Rebecca L. Greenberg , David Riddle , Morgan McNeel , Servando Rodriguez-Barajas , Michelle Yang , Blake Upshaw , Eric A. Storch
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引用次数: 1

摘要

适用于患有焦虑和/或强迫症的自闭症青年的认知行为疗法有很强的证据基础,但很少有人能获得。针对7-15岁患有焦虑和/或强迫症的自闭症青年,开发了一项为期12周的基于家庭、互联网提供的认知行为治疗(iCBT)计划,作为解决这一问题的潜在方法。在进行试点试验之前,从利益相关者(父母、青年、临床医生)那里收集了关于内容初稿的定量和定性反馈。这一反馈表明材料具有高质量、参与度、可用性和信息性。这些建议被纳入了一项试点试验中测试的治疗计划中。八个家庭被随机分配到iCBT计划中,1)每周电子邮件支持或2)每周电子邮件支助加上每两周一次的远程健康检查,其中七个家庭完成了治疗前和治疗后评估。焦虑严重程度评分平均下降39%,其中7人中有6人被归类为有反应者。初步证据表明,对于患有焦虑和/或强迫症的自闭症青年来说,基于家庭的iCBT是一种可接受且有前景的治疗方法,应在未来的工作中进一步改进和测试。
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Development and pilot testing of internet-delivered, family-based cognitive behavioral therapy for anxiety and obsessive-compulsive disorders in autistic youth

Cognitive behavioral therapy adapted for autistic youth with anxiety and/or OCD has a strong evidence base, but few have access. A 12-week family-based, Internet-delivered cognitive behavioral therapy (iCBT) program for 7-15 year-old autistic youth with anxiety and/or OCD was developed as a potential method to address this problem. Quantitative and qualitative feedback from stakeholders (parents, youth, clinicians) was gathered on an initial draft of content before conducting a pilot trial. This feedback suggested high quality, engagement, usability, and informativeness of the material. Suggestions were incorporated into the treatment program that was tested in a pilot trial. Eight families were randomized to the iCBT program with either 1) weekly email support or 2) weekly email support plus biweekly telehealth check-ins, and seven of these families completed pre- and post-treatment assessments. An average reduction of 39% in anxiety severity scores was found, with six of the seven being classified as responders. Preliminary evidence suggests that family-based iCBT is an acceptable and promising treatment for autistic youth with anxiety and/or obsessive-compulsive disorders that should be further modified and tested in future work.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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