与人类免疫缺陷病毒相关的肌肉萎缩症：运动的保护作用。

IF 4.9 2区医学 Q1 PHYSIOLOGY Exercise and Sport Sciences Reviews Pub Date : 2022-04-01 DOI:10.1249/JES.0000000000000282

Rafael Deminice, Vitor H F Oliveira, Allison R Webel, Kristine M Erlandson

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引用次数: 4

摘要

我们讨论了最近的证据，这些证据支持这样一种假设，即由于预期寿命的延长以及与艾滋病毒和治疗相关的合并症，少肌症是人类免疫缺陷病毒（HIV）患者中一个新出现的健康问题。我们还假设，在这一人群中，高强度的联合运动在控制少肌症方面发挥着关键作用，因为它直接（增加肌肉力量并刺激肥大）和间接（防止线粒体功能障碍、氧化应激和持续炎症）抵消了少肌症的特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sarcopenia Related to Human Immunodeficiency Virus: Protective Effects of Exercise.

We discuss recent evidence supporting the hypothesis that sarcopenia is an emerging health concern among people with human immunodeficiency virus (HIV) because of increasing life expectancy and HIV- and treatment-related comorbidities. We also hypothesize that combined exercise at higher intensity has a key role in managing sarcopenia in this population because it directly (increases muscle strength and stimulates hypertrophy) and indirectly (prevents mitochondrial dysfunction, oxidative stress, and persistent inflammation) counteracts sarcopenia hallmarks.

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来源期刊

Exercise and Sport Sciences Reviews 社会科学-生理学

CiteScore

10.70

自引率

1.80%

发文量

期刊介绍： Exercise and Sport Sciences Reviews made the transition from an annual hardcover series book to a quarterly journal in January 2000. The mission of this American College of Sports Medicine publication is to provide premier quarterly reviews of the most contemporary scientific, medical, and research-based topics emerging in the field of sports medicine and exercise science. The publication strives to provide the most relevant, topical information to students, professors, clinicians, scientists, and professionals for practical and research applications.