多囊卵巢综合征表型中身体质量指数与人体测量和生化参数的相关性。

IF 1.5 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Indian Journal of Clinical Biochemistry Pub Date : 2023-04-01 Epub Date: 2022-05-05 DOI:10.1007/s12291-022-01042-y
Tanuja Mehra, Sonali Sharma, Tasneem Zahra, Sapna Jangir, Barkha Gupta
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引用次数: 0

摘要

这是一项前瞻性观察研究,在拉贾斯坦邦的一家三级医疗保健中心进行。共有 68 名符合纳入和排除标准的多囊卵巢综合症(鹿特丹标准)妇女在妇产科门诊就诊,并被纳入研究。每位参与者都接受了人体测量和生化参数检查。最大的表型组是表型 A(41.17%),其次是表型 B(26.47%)、表型 C(20.58%)和表型 D(P + O)(11.76%)。高雄激素表型(A、B、C)血清葡萄糖(空腹和餐后)、血脂和血清促甲状腺激素(TSH)异常的发生率明显高于正常雄激素表型 D。
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Correlation of Body Mass Index with Anthropometric and Biochemical Parameters Among Polycystic Ovary Syndrome Phenotypes.

This was a prospective observational study, conducted at a tertiary care health centre in Rajasthan. A total of 68 women with PCOS (Rotterdam criteria) attending OPD at Department of Obstetrics and Gynecology qualified as per inclusion and exclusion criteria were included in the study. Each participant was examined for anthropometric and biochemical parameters. The largest phenotypic group was phenotype A, (41.17%); followed by B (26.47%); C (20.58%), and D (P + O) phenotypes (11.76%). Hyperandrogenic phenotypes (A, B, C), had significantly higher prevalence of deranged serum glucose (fasting and postprandial), lipid profile and serum TSH than normoandrogenic phenotype D. BMI was strongly correlated with anthropometric (p < 0.001) and biochemical parameters (p < 0.05) in phenotype A among four phenotypes of PCOS. Phenotype A was the most common form of PCOS and a strong correlation of BMI with waist circumference (WC), dyslipidemia and Sub-clinical hypothyroidism (SCH) was observed in women of this phenotype of PCOS. These results indicate that phenotype A is at increased risk of CVD and diabetes and phenotype D has least metabolic risks.

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来源期刊
Indian Journal of Clinical Biochemistry
Indian Journal of Clinical Biochemistry BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
4.50
自引率
4.80%
发文量
74
期刊介绍: The primary mission of the journal is to promote improvement in the health and well-being of community through the development and practice of clinical biochemistry and dissemination of knowledge and recent advances in this discipline among professionals, diagnostics industry, government and non-government organizations. Indian Journal of Clinical Biochemistry (IJCB) publishes peer reviewed articles that contribute to the existing knowledge in all fields of Clinical biochemistry, either experimental or theoretical, particularly deal with the applications of biochemistry, molecular biology, genetics, biotechnology, and immunology to the diagnosis, treatment, monitoring and prevention of human diseases. The articles published also include those covering the analytical and molecular diagnostic techniques, instrumentation, data processing, quality assurance and accreditation aspects of the clinical investigations in which chemistry has played a major role, or laboratory animal studies with biochemical and clinical relevance.
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