2008年越南孕妇中未发现寨卡病毒。

IF 2.4 Q3 INFECTIOUS DISEASES Tropical Diseases, Travel Medicine and Vaccines Pub Date : 2023-03-01 DOI:10.1186/s40794-023-00189-7
Y-C Chiu, D Baud, A Fahmi, B Zumkehr, M Vouga, L Pomar, D Musso, B C Thuong, M P Alves, M Stojanov
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引用次数: 1

摘要

背景:尽管寨卡病毒相关疫情于1947年首次被发现,但从2007年开始首次描述寨卡病毒相关疫情,最终在2015年拉丁美洲爆发。假设表明,该病毒已经在亚洲传播了几十年,但报告很少。方法:对2008年从越南胡志明市孕妇中分离的胎盘样本进行血清学分析和寨卡病毒筛查。结果:所有胎盘样本均未检测出寨卡病毒。176份血清样本中有4份(2.3%)特异性抑制寨卡病毒,与其他黄病毒具有不同程度的交叉反应性。虽然四个样本中的一个只抑制寨卡病毒,但不能排除与研究中未包括的其他黄病毒发生交叉反应的可能性。结论:我们的结果支持这样的结论,即在流行波的初始阶段,越南最大城市的孕妇中不存在该病毒。
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Absence of Zika virus among pregnant women in Vietnam in 2008.

Background: Despite being first identified in 1947, Zika virus-related outbreaks were first described starting from 2007 culminating with the 2015 Latin American outbreak. Hypotheses indicate that the virus has been circulating in Asia for decades, but reports are scarce.

Methods: We performed serological analysis and screened placental samples isolated in 2008 for the presence of Zika virus from pregnant women in Ho Chi Minh City (Vietnam).

Results: None of the placental samples was positive for Zika virus. Four serum samples out of 176 (2.3%) specifically inhibited Zika virus, with variable degrees of cross-reactivity with other flaviviruses. While one of the four samples inhibited only Zika virus, cross-reactivity with other flaviviruses not included in the study could not be ruled out.

Conclusion: Our results support the conclusion that the virus was not present among pregnant women in the Vietnamese largest city during the initial phases of the epidemic wave.

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来源期刊
CiteScore
5.20
自引率
0.00%
发文量
25
审稿时长
17 weeks
期刊介绍: Tropical Diseases, Travel Medicine and Vaccines is an open access journal that considers basic, translational and applied research, as well as reviews and commentary, related to the prevention and management of healthcare and diseases in international travelers. Given the changes in demographic trends of travelers globally, as well as the epidemiological transitions which many countries are experiencing, the journal considers non-infectious problems including chronic disease among target populations of interest as well as infectious diseases.
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