深入了解益生菌的组合及其对人类健康的影响。

IF 2 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Endocrine, metabolic & immune disorders drug targets Pub Date : 2024-01-01 DOI:10.2174/1871530323666230502141717
El Bethel Lalthavel Hmar, Sujata Paul, Hemanta Kumar Sharma
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引用次数: 0

摘要

人体肠道中栖息着 100-1000 多种微生物,它们主要影响宿主的内环境,因此对宿主的健康有重大影响。益生菌的最佳特征是驻留在肠道中并支持人体内部微生物群的一种或一组微生物。益生菌与增加健康优势有关,包括改善免疫功能、促进营养吸收、预防癌症和心脏相关疾病。一些研究表明,将具有互补作用的不同菌株的益生菌结合起来,可能会产生协同优势,有助于重建免疫壁龛和微生物相互作用的平衡。另一点需要记住的是,即使产品中含有更多的益生菌株,也并不总能保证其对健康的益处会更显著。要证明特定组合的合理性,必须有临床证明。益生菌菌株的临床结果与相关研究的参与者具体相关,如对成人或新生儿的研究。益生菌株的临床结果主要与研究的健康领域(如肠道健康、免疫健康、口腔健康等)相关。因此,挑选合适的益生菌至关重要,但也很棘手,因为存在多种因素,包括益生菌产品对疾病和菌株的特异性功效;然而,各种益生菌菌株具有不同的作用模式。本综述的重点是益生菌的分类、它们在增进人类健康方面的功能,以及益生菌组合对健康的潜在益处。
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An Insight into the Combination of Probiotics and their Implications for Human Health.

Over 100-1000 microbial species reside in the human gut, where they predominantly influence the host's internal environment and, thus, have a significant impact on host health. Probiotics are best characterized as a microbe or a group of microbes that reside in the gut and support the body's internal microbiota. Probiotics are linked to increased health advantages, including better immune function, improved nutritional absorption, and protection against cancer and heart-related illnesses. Several studies have demonstrated that combining probiotics from different strains with complementary activities may have synergistic advantages and aid in re-establishing the equilibrium of how immunological niches and microorganisms interact. Another thing to remember is that even though a product contains more probiotic strains, that doesn't always guarantee that the health benefits will be more significant. For specific combinations to be justified, there must be clinical proof. The clinical results of a probiotic strain are specifically pertinent to the participants in the relevant research, such as studies on adults or newborn infants. Clinical outcomes of a probiotic strain are mainly connected to the investigated health area (such as gut health, immune health, oral health, etc.). As a result, picking the right probiotic is essential yet tricky because of several factors, including probiotic products with the disease and strain-specific effectiveness exists; however, various probiotic strains have diverse modes of action. The current review focuses on probiotic categorization, their function in enhancing human health, and any potential health benefits of probiotic combinations.

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来源期刊
Endocrine, metabolic & immune disorders drug targets
Endocrine, metabolic & immune disorders drug targets ENDOCRINOLOGY & METABOLISMIMMUNOLOGY-IMMUNOLOGY
CiteScore
4.60
自引率
5.30%
发文量
217
期刊介绍: Aims & Scope This journal is devoted to timely reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.
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