从 COVID-19 早期建模中获得的启示,为英国监狱疫情管理提供参考。

IF 1.1 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH International Journal of Prisoner Health Pub Date : 2021-10-18 Epub Date: 2021-08-03 DOI:10.1108/IJPH-09-2020-0075
Declan Bays, Hannah Williams, Lorenzo Pellis, Jacob Curran-Sebastian, Oscar O'Mara, Phe Joint Modelling Team, Thomas Finnie
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引用次数: 0

摘要

目的:在这项研究中,作者介绍了在英国监狱内 COVID-19 爆发的早期建模工作中发现的一些关键结果。特别是,本研究描述了一个理想化疾病模型的输出结果,该模型模拟了在监狱环境中实施不同程度的社会干预措施时 COVID-19 的爆发动态;还描述了一个基于蒙特卡罗的模型,该模型评估了病例输入风险的降低情况,该过程要求入狱囚犯在进入普通监狱人群之前进行一段时间的自我隔离:众所周知,监狱通常将大量人口封闭在一个狭小的空间内,且混合程度较高,因此长期以来特别容易爆发疾病。为了应对 2020 年初新出现的 COVID-19 形势所带来的压力,英格兰公共卫生联合建模小组的建模人员被要求进行一些快速反应工作,以便为女王陛下监狱与缓刑犯监管局(HMPPS)可能采取的方法提供信息,从而降低病例输入和监狱环境中持续传播的风险:主要结果表明,采取社会干预措施有可能大大降低感染的总人数,同时这些措施还可以降低初始感染扩散为全监狱爆发的可能性。例如,建模显示,如果传播风险降低 50%(与未缓解的疫情相比),病例总数就会减少 98%,而这一减少也会导致 86.8% 的疫情在超过 5 人感染之前消退。此外,这项研究还发现,要求新来的人员在入院前 10 天和 14 天进行自我隔离,可分别发现 98% 和 99% 的新感染病例:在本文中,我们提出了在监狱场景中研究 COVID-19 的模型,同时也对建议的社会干预措施进行了评估。通过发表这些作品,作者希望这些方法可以帮助在更多场景中甚至在随后的疾病爆发期间对囚犯进行管理。所述方法也可随时应用于其他封闭式社区环境:原创性/价值:这些工作有助于为 HMPPS 提供信息,使其了解所述策略在 COVID-19 在英国监狱内爆发时可能产生的影响。本文所描述的工作可随时修改,用于研究一系列额外的疫情爆发情况。这些方法还有进一步发展和完善的空间,而最初项目的及时性并不允许这样做。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Insights gained from early modelling of COVID-19 to inform the management of outbreaks in UK prisons.

Purpose: In this work, the authors present some of the key results found during early efforts to model the COVID-19 outbreak inside a UK prison. In particular, this study describes outputs from an idealised disease model that simulates the dynamics of a COVID-19 outbreak in a prison setting when varying levels of social interventions are in place, and a Monte Carlo-based model that assesses the reduction in risk of case importation, resulting from a process that requires incoming prisoners to undergo a period of self-isolation prior to admission into the general prison population.

Design/methodology/approach: Prisons, typically containing large populations confined in a small space with high degrees of mixing, have long been known to be especially susceptible to disease outbreaks. In an attempt to meet rising pressures from the emerging COVID-19 situation in early 2020, modellers for Public Health England's Joint Modelling Cell were asked to produce some rapid response work that sought to inform the approaches that Her Majesty's Prison and Probation Service (HMPPS) might take to reduce the risk of case importation and sustained transmission in prison environments.

Findings: Key results show that deploying social interventions has the potential to considerably reduce the total number of infections, while such actions could also reduce the probability that an initial infection will propagate into a prison-wide outbreak. For example, modelling showed that a 50% reduction in the risk of transmission (compared to an unmitigated outbreak) could deliver a 98% decrease in total number of cases, while this reduction could also result in 86.8% of outbreaks subsiding before more than five persons have become infected. Furthermore, this study also found that requiring new arrivals to self-isolate for 10 and 14 days prior to admission could detect up to 98% and 99% of incoming infections, respectively.

Research limitations/implications: In this paper we have presented models which allow for the studying of COVID-19 in a prison scenario, while also allowing for the assessment of proposed social interventions. By publishing these works, the authors hope these methods might aid in the management of prisoners across additional scenarios and even during subsequent disease outbreaks. Such methods as described may also be readily applied use in other closed community settings.

Originality/value: These works went towards informing HMPPS on the impacts that the described strategies might have during COVID-19 outbreaks inside UK prisons. The works described herein are readily amendable to the study of a range of addition outbreak scenarios. There is also room for these methods to be further developed and built upon which the timeliness of the original project did not permit.

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来源期刊
International Journal of Prisoner Health
International Journal of Prisoner Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.80
自引率
21.40%
发文量
56
期刊最新文献
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