神经系统疾病和衰老中的代偿认知:动物和人类研究综述

IF 1.7 Q3 CLINICAL NEUROLOGY Aging brain Pub Date : 2023-01-01 DOI:10.1016/j.nbas.2022.100061
Kanishka, Sushil K. Jha
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引用次数: 1

摘要

大脑中专门的单个回路被用于特定的功能。有趣的是,多个神经回路不断相互竞争以获得特定的功能。然而,其中占主导地位的神经网络相互竞争,并成为特定功能的中枢神经网络。例如,海马体主神经回路是许多参与学习过程的主要网络。但是,在主要电路受到损坏的情况下,很多时候,次要的主导网络会补偿主要网络。这篇综述强调了在海马体缺失的情况下功能丧失的精神病理学和功能恢复方面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Compensatory cognition in neurological diseases and aging: A review of animal and human studies

Specialized individual circuits in the brain are recruited for specific functions. Interestingly, multiple neural circuitries continuously compete with each other to acquire the specialized function. However, the dominant among them compete and become the central neural network for that particular function. For example, the hippocampal principal neural circuitries are the dominant networks among many which are involved in learning processes. But, in the event of damage to the principal circuitry, many times, less dominant networks compensate for the primary network. This review highlights the psychopathologies of functional loss and the aspects of functional recuperation in the absence of the hippocampus.

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Aging brain
Aging brain Neuroscience (General), Geriatrics and Gerontology
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