综述:皮质类固醇在隐球菌性脑膜炎中的应用

IF 2.2 4区医学 Q3 MYCOLOGY Journal de mycologie medicale Pub Date : 2023-05-01 DOI:10.1016/j.mycmed.2023.101364

Junyu Liu , Jia Liu , Lu Yang, Xiaofeng Xu, Qin Bang-e, Ying Jiang, Fuhua Peng

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引用次数: 0

摘要

隐球菌性脑膜炎（CM）是一种发病率和死亡率较高的严重疾病。尽管接受皮质类固醇治疗的患者患有CM的风险很高，但皮质类固醇也被用作抗真菌药物的辅助药物，用于治疗某些情况下的CM患者（如免疫重建炎症综合征、脑cytococoma等）。在这里，我们总结了皮质类固醇在CM中应用的最新知识，旨在帮助临床医生在CM患者中合理使用皮质类固醇。

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Review: The application of corticosteroids in cryptococcal meningitis

Cryptococcal meningitis (CM) is a serious disease with high morbidity and mortality. Although the patients who received corticosteroids were at high risk of having CM, corticosteroids also have been used as an adjunct to antifungal drugs for treating people with CM in some situations (such as immune reconstitution inflammatory syndrome, cerebral cyptococcoma, et al.). Here, we summarize the current knowledge on the application of the corticosteroids in CM, aiming to help clinicians to reasonably use corticosteroids in patients with CM.

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来源期刊

Journal de mycologie medicale 医学-真菌学

CiteScore

5.10

自引率

2.80%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal de Mycologie Medicale / Journal of Medical Mycology (JMM) publishes in English works dealing with human and animal mycology. The subjects treated are focused in particular on clinical, diagnostic, epidemiological, immunological, medical, pathological, preventive or therapeutic aspects of mycoses. Also covered are basic aspects linked primarily with morphology (electronic and photonic microscopy), physiology, biochemistry, cellular and molecular biology, immunochemistry, genetics, taxonomy or phylogeny of pathogenic or opportunistic fungi and actinomycetes in humans or animals. Studies of natural products showing inhibitory activity against pathogenic fungi cannot be considered without chemical characterization and identification of the compounds responsible for the inhibitory activity. JMM publishes (guest) editorials, original articles, reviews (and minireviews), case reports, technical notes, letters to the editor and information. Only clinical cases with real originality (new species, new clinical present action, new geographical localization, etc.), and fully documented (identification methods, results, etc.), will be considered. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey platforms.