L-L-C de Oliveira, J-A-A de Arruda, M-F-P Marinho, I-L Cavalcante, L-G Abreu, A-C Abrahão, M-J Romañach, B-A-B de Andrade, M Agostini
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Additionally, electronic searches were conducted in PubMed, Embase, Scopus, Web of Science, Latin American and Caribbean Center on Health Sciences Information, and Brazilian Library of Dentistry to gather information from large case series of oral PCM.</p><p><strong>Results: </strong>Ninety-five cases of oral PCM were surveyed. The manifestations were more frequent among males (n=86/90.5%), middle-aged/older adults (n=54/58.7%), and white individuals (n=40/51.9%). The most commonly affected sites were the gingiva/alveolar ridge (n=40/23.4%) and lip/labial commissure (n=33/19.3%); however, one (n=40/42.1%) or multiple sites (n=55/57.9%) could also be affected. In 90 (94.7%) patients, \"mulberry-like\" ulcerations/moriform appearance were observed. Data from 21 studies (1,333 cases), mostly Brazilian (90.5%), revealed that men (92.4%; male/female: 11.8:1) and individuals in the fifth and sixth decades of life were the most affected (range: 7-89 years), with the gingiva/alveolar ridge, palate, and lips/labial commissure being the sites most frequently affected.</p><p><strong>Conclusions: </strong>The features of oral PCM lesions are similar to those reported in previous studies from Latin America. Clinicians should be aware of the oral manifestations of PCM, with emphasis on the clinicodemographic aspects and differential diagnoses, especially considering the phenomenon of the emergence of reported cases in rural and/or urban areas of Brazil.</p>","PeriodicalId":18351,"journal":{"name":"Medicina oral, patologia oral y cirugia bucal","volume":"28 2","pages":"e131-e139"},"PeriodicalIF":2.2000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985941/pdf/","citationCount":"2","resultStr":"{\"title\":\"Oral paracoccidioidomycosis: a retrospective study of 95 cases from a single center and literature review.\",\"authors\":\"L-L-C de Oliveira, J-A-A de Arruda, M-F-P Marinho, I-L Cavalcante, L-G Abreu, A-C Abrahão, M-J Romañach, B-A-B de Andrade, M Agostini\",\"doi\":\"10.4317/medoral.25613\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The ecoepidemiological panorama of paracoccidioidomycosis (PCM) is dynamic and still ongoing in Brazil. In particular, data about the oral lesions of PCM are barely explored. The aim of this study was to report the clinicopathological features of individuals diagnosed with oral PCM lesions at an oral and maxillofacial pathology service in Rio de Janeiro, Brazil, in the light of a literature review.</p><p><strong>Material and methods: </strong>A retrospective study was conducted on oral biopsies obtained from 1958 to 2021. Additionally, electronic searches were conducted in PubMed, Embase, Scopus, Web of Science, Latin American and Caribbean Center on Health Sciences Information, and Brazilian Library of Dentistry to gather information from large case series of oral PCM.</p><p><strong>Results: </strong>Ninety-five cases of oral PCM were surveyed. The manifestations were more frequent among males (n=86/90.5%), middle-aged/older adults (n=54/58.7%), and white individuals (n=40/51.9%). 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引用次数: 2
摘要
背景:副球孢子菌病(PCM)的生态流行病学全景是动态的,在巴西仍在进行中。特别是,关于PCM口腔病变的数据很少被探索。本研究的目的是根据文献综述,报告在巴西里约热内卢口腔颌面病理学服务中被诊断为口腔PCM病变的个体的临床病理特征。材料和方法:对1958年至2021年口腔活检进行回顾性研究。此外,在PubMed、Embase、Scopus、Web of Science、拉丁美洲和加勒比健康科学信息中心和巴西牙科图书馆进行电子检索,以收集大型口腔PCM病例系列的信息。结果:对95例口腔PCM进行了调查。男性(n=86/90.5%)、中老年人(n=54/58.7%)和白人(n=40/51.9%)多见。最常见的受累部位为牙龈/牙槽嵴(n=40/23.4%)和唇/唇连合(n=33/19.3%);然而,一个(n=40/42.1%)或多个站点(n=55/57.9%)也可能受到影响。在90例(94.7%)患者中,观察到“桑葚样”溃疡/死样外观。来自21项研究(1333例)的数据显示,男性(92.4%;男性/女性:11.8:1),年龄在50岁和60岁的个体受影响最大(范围:7-89岁),其中牙龈/牙槽嵴、上颚和嘴唇/唇连接是最常受影响的部位。结论:口腔PCM病变的特征与拉丁美洲先前的研究报告相似。临床医生应该了解PCM的口腔表现,重点是临床人口学方面和鉴别诊断,特别是考虑到巴西农村和/或城市地区报告病例的出现。
Oral paracoccidioidomycosis: a retrospective study of 95 cases from a single center and literature review.
Background: The ecoepidemiological panorama of paracoccidioidomycosis (PCM) is dynamic and still ongoing in Brazil. In particular, data about the oral lesions of PCM are barely explored. The aim of this study was to report the clinicopathological features of individuals diagnosed with oral PCM lesions at an oral and maxillofacial pathology service in Rio de Janeiro, Brazil, in the light of a literature review.
Material and methods: A retrospective study was conducted on oral biopsies obtained from 1958 to 2021. Additionally, electronic searches were conducted in PubMed, Embase, Scopus, Web of Science, Latin American and Caribbean Center on Health Sciences Information, and Brazilian Library of Dentistry to gather information from large case series of oral PCM.
Results: Ninety-five cases of oral PCM were surveyed. The manifestations were more frequent among males (n=86/90.5%), middle-aged/older adults (n=54/58.7%), and white individuals (n=40/51.9%). The most commonly affected sites were the gingiva/alveolar ridge (n=40/23.4%) and lip/labial commissure (n=33/19.3%); however, one (n=40/42.1%) or multiple sites (n=55/57.9%) could also be affected. In 90 (94.7%) patients, "mulberry-like" ulcerations/moriform appearance were observed. Data from 21 studies (1,333 cases), mostly Brazilian (90.5%), revealed that men (92.4%; male/female: 11.8:1) and individuals in the fifth and sixth decades of life were the most affected (range: 7-89 years), with the gingiva/alveolar ridge, palate, and lips/labial commissure being the sites most frequently affected.
Conclusions: The features of oral PCM lesions are similar to those reported in previous studies from Latin America. Clinicians should be aware of the oral manifestations of PCM, with emphasis on the clinicodemographic aspects and differential diagnoses, especially considering the phenomenon of the emergence of reported cases in rural and/or urban areas of Brazil.
期刊介绍:
1. Oral Medicine and Pathology:
Clinicopathological as well as medical or surgical management aspects of
diseases affecting oral mucosa, salivary glands, maxillary bones, as well as
orofacial neurological disorders, and systemic conditions with an impact on
the oral cavity.
2. Oral Surgery:
Surgical management aspects of diseases affecting oral mucosa, salivary glands,
maxillary bones, teeth, implants, oral surgical procedures. Surgical management
of diseases affecting head and neck areas.
3. Medically compromised patients in Dentistry:
Articles discussing medical problems in Odontology will also be included, with
a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients.
4. Implantology
5. Periodontology