播散性动脉粥样硬化中疫苗与COVID-19重叠1例。

Vecihe Bayrak
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引用次数: 0

摘要

2019冠状病毒病(COVID-19)已经成为我们生活的一部分,我们没有比疫苗更有效的应对方法了。COVID-19是一种引起呼吸道外严重血栓形成的疾病。疫苗也在这方面保护我们,但在某些罕见的情况下,发现接种疫苗后会形成血栓(远低于COVID-19)。在我们的案例中,有趣的是,它显示了一场灾难是如何在三种因素下发生的,这些因素会导致血栓形成。一位65岁女性弥漫性动脉粥样硬化患者以呼吸困难和吞咽困难为主诉入住重症监护病房。当日傍晚,患者于2周前接种了疫苗,她有活性COVID-19。检查时,未检测到下肢脉搏。对患者进行影像学检查和血液检查。患者出现栓塞性脑卒中、静脉及动脉血栓形成、肺栓塞、心包炎等多种并发症。本病例可考虑进行抗凝治疗研究。我们在有血栓形成风险的患者中给予有效的抗凝治疗。有血栓形成危险的患者,如弥散性动脉粥样硬化,接种疫苗后是否可以考虑抗凝治疗?
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A case report overlapped vaccine and COVID-19 in disseminated atherosclerosis.

Coronavirus disease 2019 (COVID-19) has become a part of our lives now and we have no more effective way of coping than a vaccine. COVID-19 is a disease that causes severe thrombosis outside the respiratory tract. Vaccines also protect us in this respect, but in some rare cases, thrombosis has been found to develop after vaccination (much less frequently than COVID-19). What was interesting in our case was that it showed how a disaster could happen under three factors that predispose to thrombosis. A 65-year-old female patient with disseminated atherosclerosis was admitted to the intensive care unit with complaints of dyspnea and dysphasia. In the evening of the day, the patient had the vaccination 2 weeks ago, she had active COVID-19. On examination, lower extremity pulses could not be detected. The patient's imaging and blood tests were performed. Multiple complications such as embolic stroke, venous and arterial thrombosis, pulmonary embolism, and pericarditis were observed in the patient. This case may give consideration to anticoagulant therapy studies. We give effective anticoagulant therapy in the presence of COVID-19 in patients at risk of thrombosis. Can anticoagulant therapy be considered after vaccination in patients at risk of thrombosis such as disseminated atherosclerosis?

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来源期刊
CiteScore
3.70
自引率
3.70%
发文量
29
审稿时长
8 weeks
期刊介绍: Clin Exp Vaccine Res, the official English journal of the Korean Vaccine Society, is an international, peer reviewed, and open-access journal. It covers all areas related to vaccines and vaccination. Clin Exp Vaccine Res publishes editorials, review articles, special articles, original articles, case reports, brief communications, and correspondences covering a wide range of clinical and experimental subjects including vaccines and vaccination for human and animals against infectious diseases caused by viruses, bacteria, parasites and tumor. The scope of the journal is to disseminate information that may contribute to elaborate vaccine development and vaccination strategies targeting infectious diseases and tumors in human and animals. Relevant topics range from experimental approaches to (pre)clinical trials for the vaccine research based on, but not limited to, basic laboratory, translational, and (pre)clinical investigations, epidemiology of infectious diseases and progression of all aspects in the health related issues. It is published printed and open accessed online issues (https://ecevr.org) two times per year in 31 January and 31 July. Clin Exp Vaccine Res is linked to many international databases and is made freely available to institutions and individuals worldwide
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