动物冠状病毒的抗原表位:一个小型综述。

动物疾病(英文) Pub Date : 2023-01-01 Epub Date: 2023-05-17 DOI:10.1186/s44149-023-00080-0
Mingjun Su, Guanghui Zheng, Xiangwen Xu, Houhui Song
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引用次数: 0

摘要

冠状病毒在自然界中广泛存在,可以感染哺乳动物和家禽,使其成为公共卫生问题。在全球范围内,预防和控制新出现和再次出现的动物冠状病毒是一个巨大的挑战。病毒介导的免疫反应机制对病毒预防和控制的研究具有重要意义。抗原表位是一种能够刺激抗体或致敏淋巴细胞产生的化学基团,在抗病毒免疫反应中发挥重要作用。因此,它可以为诊断方法和新型疫苗的开发提供线索。在此,我们综述了动物冠状病毒抗原表位研究的进展,旨在为动物和人类冠状病毒的预防和控制提供参考。补充信息:在线版本包含补充材料,可访问10.1186/s44149-023-00080-0。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Antigen epitopes of animal coronaviruses: a mini-review.

Coronaviruses are widespread in nature and can infect mammals and poultry, making them a public health concern. Globally, prevention and control of emerging and re-emerging animal coronaviruses is a great challenge. The mechanisms of virus-mediated immune responses have important implications for research on virus prevention and control. The antigenic epitope is a chemical group capable of stimulating the production of antibodies or sensitized lymphocytes, playing an important role in antiviral immune responses. Thus, it can shed light on the development of diagnostic methods and novel vaccines. Here, we have reviewed advances in animal coronavirus antigenic epitope research, aiming to provide a reference for the prevention and control of animal and human coronaviruses.

Supplementary information: The online version contains supplementary material available at 10.1186/s44149-023-00080-0.

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