随机环境下具有饱和发病率和疫苗接种的SVIS流行模型的平稳分布和密度函数分析。

IF 1.3 4区 生物学 Q3 BIOLOGY Theory in Biosciences Pub Date : 2023-06-01 DOI:10.1007/s12064-023-00392-2
Prasenjit Mahato, Sanat Kumar Mahato, Subhashis Das, Partha Karmakar
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引用次数: 0

摘要

本文研究了具有饱和发病率的易感-接种-感染-易感(SVIS)流行病系统的动力学性质和疫苗接种策略。通过构造合适的Lyapunov函数,研究了随机系统的存在唯一性。借助于Khas’minskii理论,我们对确定性系统的基本再生产数[公式:见文]建立了一个临界值[公式:见文]。在[公式:见文]的条件下,研究了一个唯一的遍历平稳分布。在流行病学研究中,遍历平稳分布表示该疾病将持续存在长期行为。我们的重点是利用适当的求解理论建立一般的三维福克-普朗克方程。围绕准地方性平衡,分析了随机系统的概率密度函数,这是我们研究的主题。在[公式:见文]下,遍历平稳分布和密度函数的存在都可以引出疾病持续的所有动力学行为。导出了系统的疾病消除条件。为了支持理论研究,我们讨论了数值结果和生物参数的灵敏度。突出显示结果和结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Stationary distribution and density function analysis of SVIS epidemic model with saturated incidence and vaccination under stochastic environments.

In this article, we study the dynamical properties of susceptible-vaccinated-infected-susceptible (SVIS) epidemic system with saturated incidence rate and vaccination strategies. By constructing the suitable Lyapunov function, we examine the existence and uniqueness of the stochastic system. With the help of Khas'minskii theory, we set up a critical value [Formula: see text] with respect to the basic reproduction number [Formula: see text] of the deterministic system. A unique ergodic stationary distribution is investigated under the condition of [Formula: see text]. In the epidemiological study, the ergodic stationary distribution represents that the disease will persist for long-term behavior. We focus for developing the general three-dimensional Fokker-Planck equation using appropriate solving theories. Around the quasi-endemic equilibrium, the probability density function of the stochastic system is analyzed which is the main theme of our study. Under [Formula: see text], both the existence of ergodic stationary distribution and density function can elicit all the dynamical behavior of the disease persistence. The condition of disease extinction of the system is derived. For supporting theoretical study, we discuss the numerical results and the sensitivities of the biological parameters. Results and conclusions are highlighted.

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来源期刊
Theory in Biosciences
Theory in Biosciences 生物-生物学
CiteScore
2.70
自引率
9.10%
发文量
21
审稿时长
3 months
期刊介绍: Theory in Biosciences focuses on new concepts in theoretical biology. It also includes analytical and modelling approaches as well as philosophical and historical issues. Central topics are: Artificial Life; Bioinformatics with a focus on novel methods, phenomena, and interpretations; Bioinspired Modeling; Complexity, Robustness, and Resilience; Embodied Cognition; Evolutionary Biology; Evo-Devo; Game Theoretic Modeling; Genetics; History of Biology; Language Evolution; Mathematical Biology; Origin of Life; Philosophy of Biology; Population Biology; Systems Biology; Theoretical Ecology; Theoretical Molecular Biology; Theoretical Neuroscience & Cognition.
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