真菌内生真菌土曲霉化学多样性及药用前景的研究综述。

Q1 Agricultural and Biological Sciences Fungal Biology and Biotechnology Pub Date : 2023-03-25 DOI:10.1186/s40694-023-00153-2
Khadiga Amr, Nehal Ibrahim, Ahmed M Elissawy, Abdel Nasser B Singab
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引用次数: 2

摘要

土曲霉微生物富含多种具有生物活性的次生代谢产物,是一种很有前景的药物开发资源。它促进了许多生物技术的应用,它的代谢物除了在发酵过程中有用外,还用于某些药物和食品的合成。从1987年到2022年,共鉴定出346种来自海洋和陆地的土刺藻化合物,其中172种化合物被证明具有广泛的生物活性。本综述旨在建立以不同生物活性数据为支撑的地黄次级代谢物种类的最新综合文献数据,为下一步的药物开发工作提供科学记录。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review.

Aspergillus terreus microorganism represents a promising prospective source for drug discovery since it is rich in diverse kinds of bioactive secondary metabolites. It contributed to many biotechnological applications and its metabolites are used in the synthesis of certain pharmaceuticals and food products, in addition to its useful uses in fermentation processes. There are about 346 compounds identified from marine and terrestrial-derived A. terreus from 1987 until 2022, 172 compounds of them proved a vast array of bioactivity. This review aimed to create an up-to-date comprehensive literature data of A. terreus's secondary metabolites classes supported by its different bioactivity data to be a scientific record for the next work in drug discovery.

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来源期刊
Fungal Biology and Biotechnology
Fungal Biology and Biotechnology Agricultural and Biological Sciences-Ecology, Evolution, Behavior and Systematics
CiteScore
10.20
自引率
0.00%
发文量
17
审稿时长
9 weeks
期刊最新文献
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