香港华裔妇女大队列不同影像学检查方式乳腺癌特征的比较:影像学选择对即将开展的本地筛查计划的影响

IF 1.9 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Breast Journal Pub Date : 2022-01-01 DOI:10.1155/2022/3882936
Yik Shuen Chan, Wai Ka Hung, Lok Wa Yuen, Ho Yan Yolanda Chan, Chiu Wing Winnie Chu, Polly Suk Yee Cheung
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引用次数: 1

摘要

背景:我们比较了乳房x光检查(MMG)和超声检查(USG)检测到的乳腺癌的临床、放射、病理特征,并讨论了我们最近启动的局部筛查项目选择影像学的意义。方法:回顾性研究2006年1月至2020年2月期间在香港乳腺癌登记处登记的14613名组织学证实的香港中国女性乳腺癌患者。根据乳腺癌的检测方式将患者分为四组:乳房x光和超声均可检测(MMG+/USG+)、仅乳房x光检查(MMG+/USG-)、仅超声检查(MMG-/USG+)、两者均未检测(MMG-/USG-)。比较检测到的乳腺癌的特征,包括患者人口统计学、MMG上的乳腺密度、表现方式、肿瘤大小、组织学类型和分期。对MMG+亚组的乳腺x线检查异常类型也进行了评估。结果:MMG检测到85%的癌症,USG检测到9%。MMG+/USG+癌更大,更晚期,通常有症状表现,通常表现为乳房x光检查肿块。MMG+/USG-癌更有可能表现为无症状,表现为微钙化,早期和导管原位癌。MMG-/USG+癌症更可能出现在年轻患者和乳房致密的患者中,并且更可能出现症状。MMG-/USG-癌通常较小,多发于乳腺密度较大的部位。结论:乳腺x线摄影对肿瘤的检出率较高。通过检测微钙化对早期癌症的发现具有优势。我们目前的研究表明,超声是乳腺癌检测的关键辅助工具之一。
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Comparison of Characteristics of Breast Cancer Detected through Different Imaging Modalities in a Large Cohort of Hong Kong Chinese Women: Implication of Imaging Choice on Upcoming Local Screening Program.

Background: We compared the clinico-radio-pathological characteristics of breast cancer detected through mammogram (MMG) and ultrasound (USG) and discuss the implication of the choice of imaging as the future direction of our recently launched local screening program.

Methods: Retrospective study of 14613 Hong Kong Chinese female patients with histologically confirmed breast cancer registered in the Hong Kong Breast Cancer Registry between January 2006 and February 2020. Patients were classified into four groups based on the mode of breast cancer detection (detectable by both mammogram and ultrasound (MMG+/USG+), mammogram only (MMG+/USG-), ultrasound only (MMG-/USG+), or not detectable by either (MMG-/USG-). Characteristics of breast cancer detected were compared, including patient demographics, breast density on MMG, mode of presentation, tumour size, histological type, and staging. Types of mammographic abnormalities were also evaluated for MMG+ subgroups.

Results: 85% of the cancers were detectable by MMG, while USG detected an additional 9%. MMG+/USG+ cancers were larger, more advanced in stage, often of symptomatic presentation, and commonly manifested as mammographic mass. MMG+/USG- cancers were more likely of asymptomatic presentation, manifested as microcalcifications, and of earlier stage and to be ductal carcinoma in situ. MMG-/USG+ cancers were more likely seen in young patients and those with denser breasts and more likely of symptomatic presentation. MMG-/USG- cancers were often smaller and found in denser breasts.

Conclusion: Mammogram has a good detection rate of cancers in our local population. It has superiority in detecting early cancers by detecting microcalcifications. Our current study agrees that ultrasound is one of the key adjunct tools of breast cancer detection.

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来源期刊
Breast Journal
Breast Journal 医学-妇产科学
CiteScore
4.00
自引率
0.00%
发文量
47
审稿时长
4-8 weeks
期刊介绍: The Breast Journal is the first comprehensive, multidisciplinary source devoted exclusively to all facets of research, diagnosis, and treatment of breast disease. The Breast Journal encompasses the latest news and technologies from the many medical specialties concerned with breast disease care in order to address the disease within the context of an integrated breast health care. This editorial philosophy recognizes the special social, sexual, and psychological considerations that distinguish cancer, and breast cancer in particular, from other serious diseases. Topics specifically within the scope of The Breast Journal include: Risk Factors Prevention Early Detection Diagnosis and Therapy Psychological Issues Quality of Life Biology of Breast Cancer.
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