MINOCA 和 INOCA:在心力衰竭中的作用

IF 3.8 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Current Heart Failure Reports Pub Date : 2023-06-01 Epub Date: 2023-05-18 DOI:10.1007/s11897-023-00605-1
Ana G Almeida
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引用次数: 0

摘要

审查目的:非阻塞性冠状动脉疾病的梗死(MINOCA)和缺血(INOCA)是冠状动脉综合征的最新非常规表现,在临床上得到越来越多的认可,特别是随着新的心血管成像技术的出现。两者都与心力衰竭(HF)有关。MINOCA 与良性结果无关,而心力衰竭是最常见的事件之一。关于 INOCA,微血管功能障碍也与心力衰竭有关,尤其是射血分数保留(HFpEF):最近的研究结果:无论 MINOCA 中心房颤动的病因有几种,它都可能与左心室功能障碍有关,而这种疾病的二级预防尚未明确确立。关于 INOCA,冠状动脉微血管缺血与内皮功能障碍有关,最终导致舒张功能障碍和 HFpEF。MINOCA 和 INOCA 显然与高房血症有关。在这两种情况下,都缺乏关于识别心房颤动风险因素、诊断工作的研究,更重要的是,缺乏关于适当的一级和二级预防策略的研究。
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MINOCA and INOCA: Role in Heart Failure.

Purpose of review: Infarction (MINOCA) and ischaemia (INOCA) with non-obstructive coronary disease are recent non-conventional presentations of coronary syndromes that are increasingly recognised in the clinical arena, particularly with the availability of new cardiovascular imaging techniques. Both are related to heart failure (HF). MINOCA is not associated with benign outcomes, and HF is among the most prevalent events. Regarding INOCA, microvascular dysfunction has also been found to associate with HF, particularly with preserved ejection fraction (HFpEF).

Recent findings: Regardless of the several aetiologies underlying HF in MINOCA, it is likely related to LV dysfunction, where secondary prevention is not yet clearly established. Regarding INOCA, coronary microvascular ischaemia has been associated to endothelial dysfunction leading ultimately to diastolic dysfunction and HFpEF. MINOCA and INOCA are clearly related to HF. In both, there is a lack of studies on the identification of the risk factors for HF, diagnostic workup and, importantly, the appropriate primary and secondary prevention strategies.

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来源期刊
Current Heart Failure Reports
Current Heart Failure Reports Medicine-Emergency Medicine
CiteScore
5.30
自引率
0.00%
发文量
44
期刊介绍: This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of heart failure. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as investigative, pharmacologic, and nonpharmacologic therapies, pathophysiology, and prevention. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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