{"title":"量子噪声可能限制脊椎动物身体平面图左右组织中纤毛的机械感觉敏感性","authors":"Julyan H.E. Cartwright","doi":"10.1016/j.pbiomolbio.2023.04.010","DOIUrl":null,"url":null,"abstract":"<div><p>Could nature be harnessing quantum mechanics in cilia to optimize the sensitivity of the mechanism of left–right symmetry breaking during development in vertebrates? I evaluate whether mechanosensing — i.e., the detection of a left-right asymmetric signal through mechanical stimulation of sensory cilia, as opposed to biochemical signalling — might be functioning in the embryonic left–right organizer of the vertebrate bodyplan through quantum mechanics. I conclude that there is a possible role for quantum biology in mechanosensing in cilia. The system may not be limited by classical thermal noise, but instead by quantum noise, with an amplification process providing active cooling.</p></div>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Quantum noise may limit the mechanosensory sensitivity of cilia in the left–right organizer of the vertebrate bodyplan\",\"authors\":\"Julyan H.E. Cartwright\",\"doi\":\"10.1016/j.pbiomolbio.2023.04.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Could nature be harnessing quantum mechanics in cilia to optimize the sensitivity of the mechanism of left–right symmetry breaking during development in vertebrates? I evaluate whether mechanosensing — i.e., the detection of a left-right asymmetric signal through mechanical stimulation of sensory cilia, as opposed to biochemical signalling — might be functioning in the embryonic left–right organizer of the vertebrate bodyplan through quantum mechanics. I conclude that there is a possible role for quantum biology in mechanosensing in cilia. The system may not be limited by classical thermal noise, but instead by quantum noise, with an amplification process providing active cooling.</p></div>\",\"PeriodicalId\":3,\"journal\":{\"name\":\"ACS Applied Electronic Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Electronic Materials\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0079610723000445\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Electronic Materials","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0079610723000445","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
Quantum noise may limit the mechanosensory sensitivity of cilia in the left–right organizer of the vertebrate bodyplan
Could nature be harnessing quantum mechanics in cilia to optimize the sensitivity of the mechanism of left–right symmetry breaking during development in vertebrates? I evaluate whether mechanosensing — i.e., the detection of a left-right asymmetric signal through mechanical stimulation of sensory cilia, as opposed to biochemical signalling — might be functioning in the embryonic left–right organizer of the vertebrate bodyplan through quantum mechanics. I conclude that there is a possible role for quantum biology in mechanosensing in cilia. The system may not be limited by classical thermal noise, but instead by quantum noise, with an amplification process providing active cooling.