评估世界卫生组织在印度东部一家三级护理教学医院的儿科门诊患者中使用、观察、储备抗生素和核心处方指标的情况。

Q2 Medicine Perspectives in Clinical Research Pub Date : 2023-04-01 Epub Date: 2022-07-11 DOI:10.4103/picr.picr_22_22
Pragnadyuti Mandal, Mustafa Asad, Arijit Kayal, Mohuya Biswas
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引用次数: 0

摘要

目的:本研究的目的是分析印度东部一家三级护理教学医院儿科门诊患者的抗生素处方模式,以确定世界卫生组织(世界卫生组织)获得、观察和储备(AWaRe)抗生素的使用情况,并根据世界卫生组织核心处方指标确定处方的合理性。材料和方法:收集儿科门诊患者的处方扫描件,参照世界卫生组织AWaRe分组和核心处方指标分析抗生素使用模式。结果:在3个月的研究期间,筛选出310个处方。114名接受抗生素治疗的儿童中,大多数为男性(52.64%,60),属于1-5岁年龄组(49.12%,56)。抗生素处方数量最多的是青霉素类(58.46.60%),其次是头孢菌素类(23.29%)和大环内酯类(16.54%)。大多数抗生素处方属于Access组(63.47.37%),其次为Watch组(51.38.35%)。平均每张处方的药物数量为2.66,大多数处方使用通用名(74.18%,612),58.30%(481)的药物来自世界卫生组织儿童基本药物示范清单。结论:如果需要使用抗生素,Access组的更多抗生素可用于三级护理医院门诊的门诊儿童。基于AWaRe组的指标和核心处方指标的简单组合可以消除儿童不必要的抗生素处方问题,并可能扩大抗生素管理的机会。
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Assessment of use of World Health Organization access, watch, reserve antibiotics and core prescribing indicators in pediatric outpatients in a tertiary care teaching hospital in Eastern India.

Objectives: The objective of this study was to analyze antibiotic prescribing patterns in pediatric outpatients in a tertiary care teaching hospital in Eastern India, to identify use of World Health Organization (WHO) access, watch and reserve (AWaRe) antibiotics and to identify rationality of prescribing on the basis of WHO core prescribing indicators.

Materials and methods: Scanned copies of prescriptions were collected from the pediatrics outpatients and antibiotic utilization pattern was analyzed in reference to WHO AWaRe groupings and core prescribing indicators.

Results: Over the 3 months study period, 310 prescriptions were screened. The prevalence of antibiotic use 36.77%. The majority of the 114 children who received antibiotics were males (52.64%, 60) and belonged to 1-5 year age group (49.12%, 56). The highest number of antibiotic prescriptions was from the penicillin class (58, 46.60%) followed by cephalosporin (23.29%) and macrolide (16.54%). Most number of prescribed antibiotics belonged to Access group (63, 47.37%), followed by Watch group (51, 38.35%). Average number of drugs per prescription was 2.66, percentage of encounters with injections were 0.64%. Most of the prescriptions were prescribed using generic name (74.18%, 612), 58.30% (481) of drugs were from WHO Model List of Essential Medicines for children.

Conclusion: If antibiotics are indicated, more number of antibiotics from the Access group may be used for ambulatory children who attend outpatient department of tertiary care hospitals. A simple combination of metrics based on AWaRe groups and core prescribing indicators may eliminate the problem of unnecessary antibiotic prescribing in children and may broaden the antibiotic stewardship opportunities.

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来源期刊
Perspectives in Clinical Research
Perspectives in Clinical Research Medicine-Medicine (all)
CiteScore
2.90
自引率
0.00%
发文量
41
审稿时长
36 weeks
期刊介绍: This peer review quarterly journal is positioned to build a learning clinical research community in India. This scientific journal will have a broad coverage of topics across clinical research disciplines including clinical research methodology, research ethics, clinical data management, training, data management, biostatistics, regulatory and will include original articles, reviews, news and views, perspectives, and other interesting sections. PICR will offer all clinical research stakeholders in India – academicians, ethics committees, regulators, and industry professionals -a forum for exchange of ideas, information and opinions.
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