毛囊性脱发简述

IF 1.4 Q3 DERMATOLOGY Skin Appendage Disorders Pub Date : 2023-06-01 Epub Date: 2023-03-08 DOI:10.1159/000529389
Adaeze Nwosu, Mariya Miteva
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引用次数: 0

摘要

胡须性脱发或毛囊性脱发(BAA)是毛囊性脱发的一个分支,是一种由 T 细胞介导的炎症性疾病,会破坏毛囊周期,导致毛囊衰老提前。本综述旨在帮助临床医生提高评估、诊断和处理 BAA 的技能。我们根据修改后的 PRISMA 指南,结合电子数据库中的相关关键词进行了文献综述。根据本文综述的 25 篇有关 BAA 的文章数据,BAA 主要影响中年男性(平均年龄 31 岁),他们通常会在颈部出现斑片状脱发,并在 12 个月内扩散到头皮。与 AA 相似,BAA 也与幽门螺杆菌和甲状腺炎等自身免疫性疾病有关;不过,BAA 并不像斑秃那样具有明确的遗传模式。BAA 常见的皮肤镜检查结果包括天鹅绒状白毛和感叹号毛发,这有助于将 BAA 与其他影响面部毛发的病症区分开来。在临床试验中,ALBAS 工具为临床医生提供了评估 BAA 严重程度的客观指标。直到最近,外用类固醇一直是主要的治疗方法;然而,外用和口服的janus激酶抑制剂正在取得更好的效果,平均12个月内胡须再生率高达75%。
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Alopecia Areata Barbae in a Nutshell.

Beard alopecia areata, or alopecia areata barbae, (BAA) is a subset of alopecia areata, a T-cell mediated inflammatory disease that disrupts the hair follicle cycle leading to early onset of catagen. The aim of this review is to help strengthen clinicians' skills in the evaluation, diagnosis, and management of BAA. We performed a literature review according to the modified PRISMA guidelines, using a combination of relevant key words in electronic databases. According to the data from the 25 articles on BAA reviewed here, BAA mostly affects middle-aged men (mean age 31 years) who typically experience patchy hair loss in the neck region, which spreads to the scalp within 12 months. Similar to AA, BAA is associated with autoimmune diseases such as H. pylori and thyroiditis; however, BAA has no clear genetic pattern of inheritance which is observed in alopecia areata. Common dermoscopic findings in BAA include vellus white hairs and exclamation mark hairs, which may help distinguish it from other pathologies affecting facial hair. In clinical trials, the ALBAS tool offers clinicians an objective metric to evaluate BAA severity. Until recently, topical steroids have been the mainstay therapy; however, topical and oral janus kinase inhibitors are achieving improved results, with up to 75% beard regrowth in an average of 12 months.

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来源期刊
CiteScore
2.00
自引率
10.00%
发文量
69
期刊最新文献
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