无家可归青年的认知症状与大脑变化有关。

IF 1.7 4区 医学 Q2 NURSING Clinical Nursing Research Pub Date : 2023-07-01 DOI:10.1177/10547738231168465
Dawn Bounds, Mary A Woo, Adeline Nyamathi, Priscilla Kehoe, Bhaswati Roy, Kartik Yadav, Cristina Cabrera-Mino, Rajesh Kumar
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摘要

由于各种原因,包括心理健康症状、酒精和物质使用以及不良的童年经历,受无家可归影响的青年认知能力下降。然而,可能影响无家可归青年重要认知功能的特定大脑区域的状态仍不清楚。在这项试点比较和相关研究中,对10名无家可归的男性青年和9名年龄匹配的健康男性对照组(年龄范围:18-25岁)进行了一系列人口统计学、心理、认知评估和脑磁共振成像。与对照组相比,无家可归的参与者的脑灰质组织明显减少。此外,通常与执行决策(前额叶)、抑郁(岛叶)和冲突解决(前扣带)相关的大脑区域与问卷中检测到的症状水平之间存在很强的负相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Brain Changes Linked to Cognitive Symptomatology in Homeless Youth.

Youth impacted by homelessness experience diminished cognition due to a variety of reasons including mental health symptoms, alcohol and substance use, and adverse childhood experiences. However, the status of specific brain regions which could impact important cognitive functions in homeless youth remains unclear. In this pilot comparative and correlational study, a series of demographic, psychological, cognitive assessments, and brain magnetic resonance imaging were performed in 10 male youth experiencing homelessness and 9 age-matched healthy male controls (age range: 18-25 years). Participants experiencing homelessness had significantly decreased regional brain gray matter tissue in comparison to the controls. Moreover, there were strong inverse correlations between the brain regions classically associated with executive decision-making (prefrontal cortices), depression (insular lobes), and conflict resolution (anterior cingulate), and the level of the symptoms detected by their questionnaires.

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来源期刊
CiteScore
3.40
自引率
5.90%
发文量
107
审稿时长
>12 weeks
期刊介绍: Clinical Nursing Research (CNR) is a peer-reviewed quarterly journal that addresses issues of clinical research that are meaningful to practicing nurses, providing an international forum to encourage discussion among clinical practitioners, enhance clinical practice by pinpointing potential clinical applications of the latest scholarly research, and disseminate research findings of particular interest to practicing nurses. This journal is a member of the Committee on Publication Ethics (COPE).
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