内镜在儿童复杂脑积水治疗中的作用。

Nasser M F El-Ghandour
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摘要

复杂脑积水或定位脑积水是儿科神经外科领域的一个具有挑战性的问题。为了确保治疗成功,早期诊断和治疗是至关重要的。因此,在处理早产儿和患有脑膜炎和/或脑室内出血的儿童时,儿科医生需要保持警惕。脑部CT扫描中不成比例的脑积水改变是可疑的,而钆增强多平面磁共振成像(轴位,矢状面和冠状面)是最好的诊断方式。最终的治疗方法是手术,但该方法仍有争议。囊肿开窗是治疗的主要策略,它将孤立的腔室连接在一起并与心室系统相连。囊肿开窗可以通过显微手术或内窥镜进行,以改善脑积水,减少分流次数,降低分流翻修率。然而,与显微手术相比,内窥镜手术具有简单和微创的优点。单房脑积水的预后明显优于多房脑积水;这可以归因于最初的病理疾病有助于心室区室化。由于多室脑积水预后不良,且在任何给定中心可获得的患者数量很少,因此有必要进行多中心前瞻性研究,并进行长期随访,评估结果和生活质量。
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Role of Endoscopy in Treatment of Complex Hydrocephalus in Children.

Complex hydrocephalus or loculated hydrocephalus is a challenging problem in the field of pediatric neurosurgery. Early diagnosis and treatment are paramount in order to ensure success of treatment. Therefore, alertness is required among pediatricians who are dealing with premature children and children having meningitis and/or intraventricular hemorrhage. Disproportionate hydrocephalic changes in CT scan of the brain are suspicious, whereas gadolinium-enhanced multiplanar MR imaging (axial, sagittal, and coronal) is the best diagnostic modality. The definitive treatment is surgical, yet the approach remains a matter of debate. Cyst fenestration, communicating the isolated compartments together and with the ventricular system, is the main strategy of treatment. Cyst fenestration can be performed through either microsurgery or endoscopy, in order to improve the hydrocephalus, decrease number of shunts, and reduce shunt revision rates. However, the endoscopic procedure has an advantage over microsurgery of being simple and minimally invasive. It is evident that uniloculated hydrocephalus carries better prognosis than multiloculated hydrocephalus; this can be attributed to the initial pathological disease contributing to the ventricular compartmentalization. Because of the bad prognosis in multiloculated hydrocephalus, and because there are few numbers of patients available in any given center, a multicentric prospective study with long-term follow-up evaluating the results of outcome and quality of life is warranted.

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