J Valenzuela-Mencia, M-Á Serrera-Figallo, D Torres-Lagares, G Machuca-Portillo, E Sánchez-Fernández, E Valmaseda-Castellón, M Peñarrocha-Diago, N Fernández-Mosteirín, J-M Somoza-Martin, A Pérez-Jardón, C-M Chamorro-Petronacci, A García-García
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引用次数: 0
摘要
背景:近年来,由于发达国家人均寿命的延长,全世界接受凝血功能障碍治疗,特别是接受抗凝治疗的患者人数有所增加。近年来,管理口腔外科这类患者的方案各不相同,尤其是在新型直接作用口服抗凝剂(DOAC)出现之后。对于患者、牙医和全科医生来说,如何评估这类患者在接受外科手术时的出血风险仍然是一个有争议的问题。本文件的目的是根据证据为需要接受牙科手术治疗的凝血功能障碍患者提供决策建议:根据 "国家卫生系统临床实践指南的编写。方法手册",我们召集了一批专家,就牙科外科手术(如安装种植体或拔牙)中凝血功能障碍患者的管理问题商定了 15 个 PICO 问题:15 个 PICO 问题是根据现有证据回答的,但由于缺乏对照组,大多数情况下回答的证据有限。专家们对其中两个 PICO 问题的回答是 C 级建议,而对其他问题的回答是 D 级建议:本综述的结果突出表明,有必要开展精心设计的临床试验,并设立对照组和具有代表性的样本量。
Clinical practice guideline of the spanish society of oral surgery for oral surgery in patients with coagulation disorders.
Background: The number of patients treated with coagulation disorders, and more specifically with anticoagulant therapy, has increased worldwide in recent years due to increased life expectancy in developed countries. The protocols for managing this type of patient in oral surgery has varied over recent years, especially after the appearance of new direct-acting oral anticoagulants (DOACs). The assessment of risk of bleeding in this type of patient when undergoing a surgical procedure continues to be a controversial issue for patients, dentists and general practitioners. The objective of this document is to offer recommendations, based on evidence, for decision making for patients with coagulopathies who require dental surgical intervention.
Material and methods: Based on the indications of the "Preparation of Clinical Practice guidelines in the National Health System. Methodological manual", we gathered a group of experts who agreed on 15 PICO questions based on managing patients with coagulation disorders in dental surgical procedures, such as fitting of implants or dental extractions.
Results: The 15 PICO questions were answered based on the available evidence, being limited in most cases due to the lack of a control group. Two of the PICO questions were answered by the experts with a grade C recommendation, while the rest were answered with grade D.
Conclusions: The results of this review highlight the need to undertake well designed clinical trials with control groups and with a representative sample size.
期刊介绍:
1. Oral Medicine and Pathology:
Clinicopathological as well as medical or surgical management aspects of
diseases affecting oral mucosa, salivary glands, maxillary bones, as well as
orofacial neurological disorders, and systemic conditions with an impact on
the oral cavity.
2. Oral Surgery:
Surgical management aspects of diseases affecting oral mucosa, salivary glands,
maxillary bones, teeth, implants, oral surgical procedures. Surgical management
of diseases affecting head and neck areas.
3. Medically compromised patients in Dentistry:
Articles discussing medical problems in Odontology will also be included, with
a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients.
4. Implantology
5. Periodontology