68Ga-FAPI-04肝硬化患者的PET/CT表现

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Molecular Imaging and Radionuclide Therapy Pub Date : 2023-06-20 DOI:10.4274/mirt.galenos.2022.80774

Gamze Tatar, Ediz Beyhan, Özge Erol Fenercioğlu, İsa Sevindir, Nurhan Ergül, Tevfik Fikret Çermik

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引用次数: 0

摘要

成纤维细胞活化蛋白(FAP)在肝硬化和肿瘤微环境中作为促炎性因子从纤维组织中表达。肝硬化是任何慢性肝病的最后一个阶段，肝硬化的自然过程是从无症状期发展到有症状的失代偿期，伴有腹水的发生。虽然各种临床特征表明慢性肝病患者有肝硬化，但在明确诊断之前，非侵入性方法应遵循临床方法。在此，我们报告了三例肝硬化成纤维细胞活化蛋白抑制剂(FAPI)摄取的病例，以证明68Ga-FAPI-04正电子发射断层扫描/计算机断层扫描(PET/CT)在肝硬化中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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⁶⁸Ga-FAPI-04 PET/CT Findings in Patients with Liver Cirrhosis.

Fibroblast activation protein (FAP) is expressed as a pro-inflammatory agent from fibrous tissue in liver cirrhosis and in the tumor microenvironment. Cirrhosis is the last stage of any chronic liver disease, and the natural course of cirrhosis is the progression from the asymptomatic phase to the symptomatic decompensated phase with the development of ascites. Although various clinical features suggest cirrhosis in patients with chronic liver disease, non-invasive methods should follow the clinical approach before a definitive diagnosis. Herein, we present three cases of liver cirrhosis with fibroblast activation protein inhibitor (FAPI) uptake to demonstrate the usefulness of 68Ga-FAPI-04 positron emission tomography/computed tomography (PET/CT) scan in cirrhosis.

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来源期刊

Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.30

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0.00%

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期刊介绍： Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.