疟疾流行病学和预防战略的最新情况。

IF 3.1 4区 医学 Q2 INFECTIOUS DISEASES Current Infectious Disease Reports Pub Date : 2023-06-08 DOI:10.1007/s11908-023-00805-9
Marta González-Sanz, Pedro Berzosa, Francesca F Norman
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引用次数: 1

摘要

审查目的:本次审查的目的是提供全球和非流行地区最近疟疾流行病学的最新情况,以确定遗传多样性疟原虫物种的当前分布和影响,并总结最近实施的干预和预防工具。最近的发现:近年来,疟疾流行病学发生了显著变化,2020-2021年全球总病例和死亡人数有所增加,部分原因是新冠肺炎大流行。在新的地区出现抗青蒿素的物种,以及携带pfhrp2/3基因缺失的寄生虫的分布不断扩大,都令人担忧。遏制这种感染负担的新策略,如疫苗接种,已经在某些流行地区实施,目前正在评估其表现。摘要:流行地区对疟疾控制不力可能会对输入性疟疾产生影响,必须采取措施防止在无疟疾地区再次传播。加强对疟原虫的监测和调查。基因变异将有助于未来疟疾的成功诊断和治疗。还应加强采用“一个健康”综合办法控制疟疾的新战略。
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Updates on Malaria Epidemiology and Prevention Strategies.

Purpose of review: The objective of this review was to provide an update on recent malaria epidemiology, both globally and in non-endemic areas, to identify the current distribution and repercussions of genetically diverse Plasmodium species and summarize recently implemented intervention and prevention tools.

Recent findings: Notable changes in malaria epidemiology have occurred in recent years, with an increase in the number of total cases and deaths globally during 2020-2021, in part attributed to the COVID-19 pandemic. The emergence of artemisinin-resistant species in new areas and the expanding distribution of parasites harbouring deletions of the pfhrp2/3 genes have been concerning. New strategies to curb the burden of this infection, such as vaccination, have been implemented in certain endemic areas and their performance is currently being evaluated.

Summary: Inadequate control of malaria in endemic regions may have an effect on imported malaria and measures to prevent re-establishment of transmission in malaria-free areas are essential. Enhanced surveillance and investigation of Plasmodium spp. genetic variations will contribute to the successful diagnosis and treatment of malaria in future. Novel strategies for an integrated One Health approach to malaria control should also be strengthened.

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来源期刊
Current Infectious Disease Reports
Current Infectious Disease Reports INFECTIOUS DISEASES-
CiteScore
6.70
自引率
0.00%
发文量
19
期刊介绍: This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of infectious disease. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as HIV/AIDS, sexually transmitted diseases, tropical and travel medicine, and urinary tract infections. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists.
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