预防食物过敏:2023 年我们在哪里?

IF 1.6 Q3 ALLERGY Asia Pacific Allergy Pub Date : 2023-03-01 Epub Date: 2023-04-28 DOI:10.5415/apallergy.0000000000000001
Carina Venter, Peter K Smith, David M Fleischer
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摘要

食物过敏的预防包括建议孕妇在怀孕和哺乳期间的饮食、生命早期的喂养和固体食物的引入。不建议孕妇和哺乳期妇女在饮食中排除任何食物过敏原,但缺乏数据支持为预防食物过敏而主动摄入食物过敏原。建议母乳喂养对母亲和孩子的健康有很多好处,但并没有显示母乳喂养与减少儿童食物过敏有任何关联。目前还没有关于使用任何婴儿配方奶粉来预防过敏的建议,包括使用部分水解或广泛水解的配方奶粉。一旦开始添加固体食物,根据随机对照试验,建议在婴儿饮食中尽早积极添加花生和鸡蛋,并继续食用这些食物。虽然有关其他主要食物过敏原的数据有限,也不知道早期引入是否可以预防过敏的发生,但没有必要推迟在婴儿饮食中引入这些过敏原。目前还没有研究从饮食文化习俗的角度来解释食物过敏原的摄入量,但在婴儿 1 岁之前让其接触家庭食物是合理的。摄入典型的西方饮食和高糖化终产物食物可能与食物过敏的增加有关。同样,在预防食物过敏方面,母婴饮食中微量营养素(如维生素 D 和欧米加-3 脂肪酸)的摄入量也需要进一步明确。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Food allergy prevention: Where are we in 2023?

Food allergy prevention involves recommendations to the maternal diet during pregnancy and breast feeding, early life feeding and introduction of solid foods. Pregnant and breastfeeding women are not recommended to exclude any food allergens from their diet, but data are lacking to support active consumption of food allergens for prevention of food allergy. Breastfeeding is recommended for the many health benefits to the mother and child but has not shown any association with reduction in childhood food allergies. There is currently no recommendation regarding the use of any infant formula for allergy prevention, including the use of partially or extensively hydrolyzed formulas. Once the introduction of solid food commences, based on randomized controlled trials, it is advised to actively introduce peanuts and egg early into the infant diet and continue with consumption of these. Although there are limited data with respect to other major food allergens and whether early introduction may prevent allergy development, there is no need to delay the introduction of these allergens into the infant diet. Interpreting food allergen consumption in the context of cultural food practices has not been studied, but it makes sense to introduce the infant to family foods by 1 year of age. Consumption of foods typical of the Western diet and foods high in advanced glycation end products may be associated with an increase in food allergies. Similarly, intake of micronutrients, such as vitamin D and omega-3 fatty acids in both the maternal and infant diet, needs further clarification in the context of food allergy prevention.

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来源期刊
CiteScore
2.50
自引率
5.90%
发文量
33
期刊介绍: Asia Pacific Allergy (AP Allergy) is the official journal of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). Although the primary aim of the journal is to promote communication between Asia Pacific scientists who are interested in allergy, asthma, and clinical immunology including immunodeficiency, the journal is intended to be available worldwide. To enable scientists and clinicians from emerging societies appreciate the scope and intent of the journal, early issues will contain more educational review material. For better communication and understanding, it will include rational concepts related to the diagnosis and management of asthma and other immunological conditions. Over time, the journal will increase the number of original research papers to become the foremost citation journal for allergy and clinical immunology information of the Asia Pacific in the future.
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