新冠肺炎疫苗接种后自身免疫性肝炎35例临床分析

IF 1.9 Q3 PHARMACOLOGY & PHARMACY Drug Discoveries and Therapeutics Pub Date : 2023-07-12 DOI:10.5582/ddt.2023.01022
Meirong Wang, Juan Qi, Yujuan Liu
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引用次数: 0

摘要

2019冠状病毒病(COVID-19)疫苗已被证明可有效保护人们免受严重疾病进展、住院和死亡。然而,在世界范围内已经报道了各种各样的副作用。自身免疫性肝炎(AIH)的新发或突然发作是COVID-19疫苗接种后极为罕见的不良事件,大多数病例表现为轻微症状。不幸的是,有一些致命的并发症。在这篇小型综述中,我们总结了目前报道的35例COVID-19疫苗接种后AIH的临床特征,并提示自身免疫性疾病患者接种疫苗后发生AIH的风险更高。
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Autoimmune hepatitis following COVID-19 vaccination: Clinical characteristics of 35 reported cases.

The coronavirus disease 2019 (COVID-19) vaccines have been shown to be effective in protecting people from severe disease progression, hospitalisation and death. However, a wide range of side effects have been reported worldwide. New onset or flare-up of autoimmune hepatitis (AIH) is an extremely rare adverse event following COVID-19 vaccination, with the majority of cases presenting with mild symptoms. Unfortunately, there have been cases of fatal complications. In this mini-review, we have summarised the clinical characteristics of a total of 35 currently reported cases of AIH after COVID-19 vaccination and suggest that patients with autoimmune diseases may be at higher risk of developing AIH after vaccination.

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来源期刊
Drug Discoveries and Therapeutics
Drug Discoveries and Therapeutics PHARMACOLOGY & PHARMACY-
CiteScore
3.20
自引率
3.20%
发文量
51
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