心脏移植手术量与肺移植项目的存在及心脏移植 SRTR 一年生存率的关系。

IF 1.3 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Thoracic and Cardiovascular Surgeon Pub Date : 2024-06-01 Epub Date: 2023-05-17 DOI:10.1055/a-2095-6636
Jake L Rosen, Danial Ahmad, Anjali Uphadyaya, Andrew T Brodie, Gabriel Gaw, Indranee Rajapreyar, J Eduardo Rame, Rene J Alvarez, Keshava Rajagopal, John W Entwistle, Howard T Massey, Vakhtang Tchantchaleishvili
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引用次数: 0

摘要

背景:影响心脏移植(HTx)和肺移植(LTx)计划结果的因素有很多。机构和社区特征的差异已被证明会影响存活率。目前,美国有一半的心脏移植中心没有同时开展肺移植项目。本研究旨在更好地了解有LTx计划和无LTx计划的移植中心的特点:2020年8月,移植受者科学注册中心(SRTR)收集了全国范围内的移植数据。SRTR 星级从第 1 级(最低)到第 5 级(最高)不等。比较了纯心脏(H0)项目中心和心肺(HL)项目中心的移植量和SRTR生存率星级:有117个移植中心获得了SRTR星级评定,并报告了一次或多次心脏移植手术。一年内进行 HTx 的中位数为 16 例(四分位数间距 [IQR]:2-29)。HL中心的数量(n = 67,57.3%)与H0中心(n = 50,42.7%;p = 0.14)相当。HL中心的热疗量(28 [IQR:17-41])超过了H0中心的热疗量(13 [IQR:9-23];P = 0.25)。H0和HL中心的HTx一年生存率中位数均为3(IQR:2-4)(P = 0.85)。HTx和LTx手术量与各自的1年存活率呈正相关(p 结论:HTx和LTx手术量与1年存活率呈正相关:虽然LTx项目的存在与HTx存活率没有直接关系,但它与HTx数量呈正相关。高温热处理和低温热处理量与 1 年存活率呈正相关。
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Association of Heart Transplant Volume with Presence of Lung Transplant Programs and Heart Transplant's SRTR One-year Survival Rating.

Background:  Several factors affect heart transplant (HTx) and lung transplant (LTx) program outcomes. Variabilities in institutional and community characteristics have been shown to influence survival. At present, half of HTx centers in the United States do not possess a concomitant LTx program. This study sought to better understand the characteristics of HTx with and without LTx programs.

Methods:  Nationwide transplant data were collected from the Scientific Registry of Transplant Recipients (SRTR) in August 2020. SRTR star rating ranges from tier 1 (lowest) to tier 5 (highest). HTx volumes and SRTR star ratings for survival were compared between the centers with heart-only (H0) programs and the centers with heart-lung (HL) programs.

Results:  SRTR star ratings were available for 117 transplant centers with one or more HTx reported. The median number of HTx performed over 1 year was 16 (interquartile range [IQR]: 2-29). The number of HL centers (n = 67, 57.3%) were comparable to H0 centers (n = 50, 42.7%; p = 0.14). The HTx volume at the HL centers (28 [IQR: 17-41]) exceeded the HTx volume at the H0 centers (13 [IQR: 9-23]; p < 0.01), but were comparable to the LTx volume at the HL centers (31 [IQR: 16-46]; p = 0.25). The median HTx one-year survival rating was 3 (IQR: 2-4) at both the H0 and HL centers (p = 0.85). The HTx and LTx volumes were positively associated with the respective 1-year survivals (p < 0.01).

Conclusion:  While the presence of an LTx program is not directly associated with HTx survival, it has a positive association with the HTx volume. The HTx and LTx volumes are positively associated with the 1-year survival.

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来源期刊
CiteScore
3.40
自引率
6.70%
发文量
365
审稿时长
3 months
期刊介绍: The Thoracic and Cardiovascular Surgeon publishes articles of the highest standard from internationally recognized thoracic and cardiovascular surgeons, cardiologists, anesthesiologists, physiologists, and pathologists. This journal is an essential resource for anyone working in this field. Original articles, short communications, reviews and important meeting announcements keep you abreast of key clinical advances, as well as providing the theoretical background of cardiovascular and thoracic surgery. Case reports are published in our Open Access companion journal The Thoracic and Cardiovascular Surgeon Reports.
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