来自两个英国转诊中心的37只手术治疗的截瘫、深痛阴性的法国斗牛犬的胸腰椎间盘突出病例系列。

IF 1.3 Q2 VETERINARY SCIENCES Veterinary Record Open Pub Date : 2023-05-09 eCollection Date: 2023-06-01 DOI:10.1002/vro2.61
Gareth Michael Couper Jones, Giunio Bruto Cherubini, Francisco Llabres-Diaz, Abby Caine, Alberta De Stefani
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引用次数: 0

摘要

背景:胸腰椎间盘突出症(TL IVDEs)是犬常见的脊柱疾病,尤其是软骨营养不良犬种。在患有TL-IVDE的狗中,深度疼痛感知的丧失是一个有充分记录的负面预后指标。本研究的目的是报告经手术治疗的截瘫深痛感知阴性法国斗牛犬TL-IVDE患者的深痛感知和独立行走的恢复率。回顾了医疗和MRI记录,包括以下定量MRI变化:病变长度、脊髓肿胀程度和脊髓压迫的严重程度。结果:37只法国斗牛犬符合入选标准,37只斗牛犬中有14只(38%)在出院时(中位住院10.0天[四分位间距7.0-15.5天])恢复了深度疼痛感,两只斗牛犬独立行走(6%)。37只狗中有10只在住院期间被实施了安乐死。与T3-L3病变的21只狗中的11只(52%)相比,L4-S3病变的狗中恢复深痛觉的数量明显减少(3/16,19%)(p=0.048)。定量MRI变化与深痛觉的恢复无关。出院后,经过中位1个月的随访期,另外三只狗恢复了深度疼痛感,五只狗独立活动(分别为17/37[46%]和7/37[19%])。结论和临床重要性:这项研究为以下论点提供了支持:与其他品种相比,患有TL-IVDE的法国斗牛犬手术后的恢复较差;指出了进一步的前瞻性、品种对照研究。
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A case series of 37 surgically managed, paraplegic, deep pain negative French bulldogs, with thoracolumbar intervertebral disc extrusion, from two English referral centres.

Background: Thoracolumbar intervertebral disc extrusions (TL-IVDEs) are a common spinal disorder in dogs, especially within chondrodystrophic breeds. Loss of deep pain perception is a well-documented negative prognostic indicator in dogs with TL-IVDE. The objectives of this study were to report the rate of return of deep pain perception and independent ambulation in surgically treated, paraplegic, deep pain perception negative French bulldogs with TL-IVDEs.

Methods: A retrospective case series of deep pain perception negative dogs with TL-IVDE presenting to two referral centres between 2015 and 2020 was conducted. Medical and MRI records were reviewed, including the following quantitative MRI changes: lesion length, extent of spinal cord swelling and severity of spinal cord compression.

Results: Thirty-seven French bulldogs met the inclusion criteria, with 14 of 37 (38%) regaining deep pain perception by the time of discharge (median hospitalisation 10.0 days [interquartile range 7.0-15.5 days]) with two dogs independently ambulatory (6%). Ten of the 37 dogs were euthanased during hospitalisation. Significantly fewer dogs (3/16, 19%) with L4-S3 lesions regained deep pain perception compared to 11 of 21 (52%) of dogs with T3-L3 lesions (p = 0.048). Quantitative MRI changes were not associated with the return of deep pain perception. After discharge, with a median 1-month follow-up period, an additional three dogs regained deep pain perception and five dogs became independently ambulatory (17/37 [46%] and 7/37 [19%], respectively).

Conclusions and clinical importance: This study adds support to the contention that the recovery of French bulldogs with TL-IVDE from surgery is poor compared with other breeds; further prospective, breed-controlled studies are indicated.

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来源期刊
Veterinary Record Open
Veterinary Record Open VETERINARY SCIENCES-
CiteScore
3.00
自引率
0.00%
发文量
25
审稿时长
19 weeks
期刊介绍: Veterinary Record Open is a journal dedicated to publishing specialist veterinary research across a range of topic areas including those of a more niche and specialist nature to that considered in the weekly Vet Record. Research from all disciplines of veterinary interest will be considered. It is an Open Access journal of the British Veterinary Association.
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