接种 COVID-19 mRNA 疫苗后的并发症--病例报告和简短综述。

Q4 Medicine Vnitrni lekarstvi Pub Date : 2023-01-01 DOI:10.36290/vnl.2023.054
Ivan Varga, Peter Michalka, Jana Poláková Mištinová
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引用次数: 0

摘要

由 SARS-CoV-2 冠状病毒(严重急性呼吸系统综合征冠状病毒 2)引起的 COVID-19 (COronaVIrus Disease 2019)疾病大流行导致数百万人死亡,许多患者在度过急性期后出现慢性后遗症。为了阻止病毒的传播,人们研制了多种疫苗,但这些疫苗可能会产生严重的不良反应。我们报告了一例患者在接种第二剂 mRNA 疫苗 BNT162b2 (Comirnaty®) 后出现急性(心肌炎、支气管哮喘加重)和长期(体位性正位性心动过速综合征 - POTS)并发症的病例。治疗包括调理措施、多种药物疗法(美托洛尔、伊伐布雷定、皮质类固醇、抗组胺药、抗组胺药、支气管扩张剂)和多种保健品(海松皮提取物、槲皮素、维生素、镁、磷脂酰胆碱)。在讨论中,我们分析了接种疫苗后的损伤,并对目前的文献进行了简短回顾。
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Complications after administration of mRNA vaccine against COVID-19 - case report and short review.

The pandemic of the disease COVID-19 (COronaVIrus Disease 2019) caused by the SARS-CoV-2 coronavirus (severe acute respiratory syndrome coronavirus 2) resulted in millions of deaths and many patients have chronic consequences after overcoming the acute condition. Several vaccines have been developed in an effort to stop the spread of the virus, but they have potentially serious adverse effects. We present a case report of a patient with acute (myocarditis, exacerbation of bronchial asthma) and long-term (postural orthostatic tachycardia syndrome - POTS) complications after vaccination with the second dose of mRNA vaccine BNT162b2 (Comirnaty®). Treatment consists of regimen measures, numerous pharmacotherapy (metoprolol, ivabradine, corticosteroids, antihistamines, antiphlogistics, bronchodilators) and several nutraceuticals (maritime pine bark extract, quercetin, vitamins, magnesium, phosphatidylcholine). In the discussion, we analyze post-vaccination injury and present a short review of the current literature.

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来源期刊
Vnitrni lekarstvi
Vnitrni lekarstvi Medicine-Internal Medicine
CiteScore
0.50
自引率
0.00%
发文量
104
期刊介绍: Vnitřní lékařství je tiskovým orgánem České internistické společnosti České lékařské společnosti Jana Evangelisty Purkyně a Slovenskej internistickej spoločnosti Slovenskej lekárskej spoločnosti. Je vydáván nepřetržitě od roku 1955. Časopis vychází jako měsíčník, tedy 12krát do roka a podle potřeby jsou v běžném ročníku vydávána jeho suplementa, která jsou obsahově zaměřena k určitému tématu. Tematicky je časopis zaměřen široce na oblast interní medicíny se zvláštní pozorností ke kardiologii, diabetologii a poruchám metabolizmu.
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