常染色体显性多囊肾患者在肾移植时的下极原生肾囊肿去顶。

IF 1.5 4区 医学 Q3 UROLOGY & NEPHROLOGY Urology Journal Pub Date : 2023-07-26 DOI:10.22037/uj.v20i.7047
Abbas Basiri, Nasser Simforoosh, Amirhossein Nayebzade, Hamed Marufi, Amir Hossein Kashi
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引用次数: 0

摘要

报告我们对5例成人型多囊肾(ADPKD)患者进行同种异体肾移植干扰下极原生肾囊肿的同侧下极肾囊肿去顶术的经验。在所有这些患者中,原生肾脏延伸到同侧骨盆,双侧ADPKD在大体检查时引起腹部增大。在同种异体移植的同一阶段进行下极肾囊肿的切除。在观察同种异体移植对肾下极囊肿的干扰后,决定切除同侧肾下极囊肿。在患者A中,在与患者协商后,在肾移植后6周进行双侧原生肾切除术,当时有证据表明同种异体移植物功能良好,受体正在服用低剂量的免疫抑制药物。在其他患者中,没有必要进行原位肾切除术。这一经验提示,当大的同侧肾囊肿影响同种异体移植的安全植入时,可以选择在同一疗程进行囊肿去顶并继续同种异体移植。在许多患者中,不需要进行原生肾切除术,如果认为有必要,将在有证据表明同种异体移植功能良好,患者肾功能良好,免疫抑制药物剂量低,手术风险较小时进行。据我们所知,文献中没有这样的报道。
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Unroofing of Lower Pole Native Kidney Cysts in Patients with Autosomal Dominant Polycystic Kidneys at the Time of Kidney Transplantation.

To report our experience with unroofing of ipsilateral lower pole kidney cysts in five patients with adult-type polycystic kidneys [ADPKD] when free implantation of kidney allograft interfered with lower pole native kidney cysts. In all of these patients, the native kidneys extended to the ipsilateral pelvis and bilateral ADPKD caused enlargement of the abdomen on gross examination. Unroofing of lower pole kidney cysts was performed during the same session of allograft transplantation. The decision to unroof lower pole cysts of the ipsilateral kidney was made after observing interference of lower pole cysts with free implantation of the allograft. In patient A, bilateral native nephrectomy was performed 6 weeks after kidney transplantation after consultation with the patient, when there was evidence of the good function of the allograft and the recipient was on a low dose of immunosuppressive medications. In other patients, no need for native nephrectomy observed. This experience suggests the possibility that when large ipsilateral kidney cysts interfere with safe implantation of the allograft, there is an option of performing cyst unroofing at the same session and proceeding with allograft implantation. In many patients, there would be no need for native nephrectomy and of deemed necessary, it will be performed later, when there is evidence of the good function of the allograft and the patient is on good kidney function with a low dose of immunosuppressive medications and a less risk profile for the operation. To our best knowledge, there is no prior such report in the literature.

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来源期刊
Urology Journal
Urology Journal UROLOGY & NEPHROLOGY-
CiteScore
2.60
自引率
6.70%
发文量
44
审稿时长
6-12 weeks
期刊介绍: As the official journal of the Urology and Nephrology Research Center (UNRC) and the Iranian Urological Association (IUA), Urology Journal is a comprehensive digest of useful information on modern urology. Emphasis is on practical information that reflects the latest diagnostic and treatment techniques. Our objectives are to provide an exceptional source of current and clinically relevant research in the discipline of urology, to reflect the scientific work and progress of our colleagues, and to present the articles in a logical, timely, and concise format that meets the diverse needs of today’s urologist. Urology Journal publishes manuscripts on urology and kidney transplantation, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. Accordingly, original articles, case reports, and letters to editor are encouraged.
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