荧光素钠对脉络膜血管指数的短期影响。

IF 1.6 4区 医学 Q3 OPHTHALMOLOGY Cutaneous and Ocular Toxicology Pub Date : 2023-09-01 DOI:10.1080/15569527.2023.2227894
Selim Cevher, Mehmet Barış Üçer, Mustafa Duran
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引用次数: 0

摘要

目的:探讨荧光素钠对脉络膜血管指数(CVI)的影响。材料和方法:在这项横断面研究中,27例轻度非增殖性糖尿病视网膜病变(无黄斑病变和任何系统性疾病)患者进行荧光素血管造影(FA)手术,共27只眼。应用光学相干层析成像及二值化技术分别于基线及术后第5、15、30分钟检测脉络膜厚度(CT)、总脉络膜面积(TCA)、管腔面积(LA)、基质面积(SA)、LA/SA、CVI等脉络膜参数。比较了手术前后各参数的取值。结果:基线时TCA、LA、SA、LA/SA、CVI平均值分别为0.44±0.14mm2、0.29±0.09 mm2、0.15±0.05 mm2、1.87±0.19。FA后5 min, TCA、LA、SA、LA/SA、CVI平均值分别为0.43±0.13 mm2、0.28±0.08 mm2、0.15±0.05 mm2、1.82±0.20、0.64±0.03。FA后5 min LA和CVI值显著降低(p:0.002和p:0.021)。FA前鼻部、中央凹下、颞部CT平均为279.22±93.40 μm、289.78±91.17 μm、267.44±95.71 μm, FA后5 min分别为270.33±90.34 μm、279.67±90.01 μm、261.82±95.82 μm (p = 0.960、p = 0.952、p = 0.991)。虽然CT值有所降低,但FA前后的差异无统计学意义。结论:本研究显示,轻度非增殖性糖尿病视网膜病变患者FA后5分钟LA和CVI值显著下降。
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Short time effect of sodium fluorescein on chorodial vascularity index.

Purpose: This study aimed to investigate the effect of sodium fluorescein on the choroidal vascularity index (CVI).

Materials and methods: In this cross-sectional study, a total of 27 eyes of 27 mild nonproliferative diabetic retinopathy patients (without maculopathy and any systemic disease) who performed fluorescein angiography (FA) procedure were included. Choroidal parameters such as choroidal thickness (CT), total choroidal area (TCA), luminal area (LA), stromal area (SA), LA/SA, and CVI were examined with the optical coherence tomography and binarization technique at baseline and 5th, 15th, and 30th minutes after FA. The values of the parameters before and after the procedure were compared.

Results: At baseline, the mean values of the TCA, LA, SA, LA/SA, and CVI were 0.44 ± 0.14mm2, 0.29 ± 0.09 mm2, 0.15 ± 0.05 mm2, 1.87 ± 0.19. Five minutes later to FA, the mean values of the TCA, LA, SA, LA/SA, and CVI were 0.43 ± 0.13 mm2, 0.28 ± 0.08 mm2, 0.15 ± 0.05 mm2, 1.82 ± 0.20, and 0.64 ± 0.03, respectively. There was a significant decrease in LA and CVI values 5 minutes after FA (p:0.002 and p:0.021, respectively). On the other hand, the mean, nasal, subfoveal, and temporal CT were 279.22 ± 93.40 μm, 289.78 ± 91.17 μm, 267.44 ± 95.71 μm before FA and 270.33 ± 90.34 μm, 279.67 ± 90.01 μm, 261.82 ± 95.82 μm 5 minutes after FA (p = 0.960, p = 0.952, and p = 0.991, respectively). Although there was a reduction in the value of CT, there was not a statistically significant difference between before and after FA.

Conclusions: This study shows that there was a significant decrease in LA and CVI values 5 minutes after FA in patients with mild nonproliferative diabetic retinopathy.

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来源期刊
CiteScore
3.30
自引率
6.20%
发文量
40
审稿时长
1 months
期刊介绍: Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures. In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.
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