阿替巴拉果实的生药学和植物化学研究。

Ayu Pub Date : 2021-07-01 Epub Date: 2023-04-12 DOI:10.4103/ayu.AYU_264_20
Rajesh Bolleddu, Sama Venkatesh, Ch V Narasimhaji, Jayram Hazra
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引用次数: 1

摘要

背景:洋地黄(锦葵科),俗称“阿替巴拉”,是一种具有重要药用价值的植物。该植物具有冷却、通便、消化、镇痛、抗炎、收敛、利尿、祛痰、抗过敏、壮阳和镇痛等多种有益作用,在阿育吠陀医学体系中广泛使用。目的:建立洋地黄果实的宏观、粉末显微镜及理化分析方法。材料和方法:本研究建立了洋地黄果实的生药学研究,包括形态评价、粉末显微镜、灰分值、外来有机物、提取值、植物化学、荧光研究和高效薄层色谱指纹图谱等参数。结果:果实粉末显微镜显示出不同大小的星状毛、种皮、木质化的内果皮和栅栏细胞等诊断特征。果粉的干燥值损失为7.7%w/w。相对于空气干燥的粗药物,发现药物的总灰分值为10.5%,酸不溶性灰分为2.4%w/w。发现水溶性和醇溶性提取物分别为9.64%w/w和9.04%w/w。结论:洋地黄水提物和醇提物的植物化学特征表明其含有蛋白质、碳水化合物、酚类、黄酮类、皂苷和类固醇。本研究中观察到的粉末显微镜和植物化学研究可以作为鉴定印度洋地黄果实的宝贵资源。
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Pharmacognostical and phytochemical studies of Atibala (Abutilon indicum [Linn.] sweet) fruit.

Background: Abutilon indicum (Linn.) Sweet (Malvaceae), generally called as "Atibala" is a plant of high medicinal importance. The plant possesses several beneficial effects such as cooling, laxative, digestive, analgesic, anti-inflammatory, astringent, diuretic, expectorant, antihelmintic, aphrodisiac, and demulcent which is widely used in the Ayurveda system of medicine.

Aim: The current study is aimed to establish the macroscopy, powder microscopy and physicochemical analysis of A. indicum fruits.

Materials and methods: The Pharmacognostical studies on A. indicum fruits, including parameters such as morphological evaluation, powder microscopy, ash values, foreign organic matter, extractive value, phytochemical, fluorescence studies, and high-performance thin-layer chromatography fingerprint profile, are established in the current study.

Results: Fruit powder microscopy has shown diagnostic characteristics such as stellate hairs of different sizes, testa, lignified endocarp, and palisade cells. The loss on drying value of fruit powder was 7.7% w/w. The total ash values of the drug were found to be 10.5% and acid insoluble ash 2.4% w/w with respect to the air-dried crude drug. Water-soluble and alcohol-soluble extractives were found to be 9.64% w/w and 9.04% w/w, respectively.

Conclusion: Phytochemical characterization of aqueous, alcoholic extracts of A. indicum fruit revealed the presence of proteins, carbohydrates, phenols, flavonoids, saponins, and steroids. The powder microscopical and phytochemical studies observed in this study can serve as a valuable resource for the authentication of A. indicum fruits.

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