Do the mammillary bodies atrophy with aging? A magnetic resonance imaging study.

IF 1.2 4区医学 Q3 ANATOMY & MORPHOLOGY Surgical and Radiologic Anatomy Pub Date : 2023-11-01 Epub Date: 2023-07-14 DOI:10.1007/s00276-023-03205-9

Satoshi Tsutsumi, Natsuki Sugiyama, Hideaki Ueno, Hisato Ishii

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Abstract

Purpose: This retrospective study aimed to explore age-related atrophy of the mammillary bodies (MBs) based on their temporal change using magnetic resonance imaging (MRI).

Materials and methods: The study included 30 adult outpatients who presented to the hospital and were followed for more than 100 months with annual MRIs. The bi-ventricular width (BVW), third ventricle width (TVW), and bi-mammillary dimension (BMD) were measured on axial T2-weighted imaging and analyzed.

Results: The 30 patients comprised 1 in their 40s, 5 in their 50s, 6 in their 60s, 11 in their 70s, 5 in their 80s, and 2 in their 90s. The MBs were consistently detected with left-to-right symmetry. The mean BVW was 32 ± 2.2 mm on the initial (BVW1) and 32 ± 2.4 mm on the last (BVW2) MRI. The mean TVW was 7.0 ± 2.3 mm on the initial (TVW1) and 7.6 ± 2.7 mm on the last (TVW2) MRI. Furthermore, the mean BMD was 9.9 ± 1.3 mm on the initial (BMD1) and 10 ± 1.3 mm on the last (BMD2) MRI. Statistically, no age ranges had a large dimension for BVW1, BVW2, TVW1, TVW2, BMD1, or BMD2. Changes between TVW1 and TVW2 were significantly different in the patients in their 80s; changes between BMD1 and BMD2 were not different for any age range or between sexes.

Conclusions: Aging alone does not seem to promote MB atrophy. In healthy brains, the MBs may be stationary structures throughout life.

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乳头体会随着年龄的增长而萎缩吗？磁共振成像研究。

目的：本回顾性研究旨在利用磁共振成像（MRI），根据时间变化，探讨与年龄相关的乳头体萎缩。材料和方法：该研究包括30名成年门诊患者，他们在医院就诊，并接受了超过100个月的年度磁共振成像随访。在轴向T2加权成像上测量并分析双心室宽度（BVW）、第三心室宽度（TVW）和双乳头尺寸（BMD）。结果：30名患者包括1名40多岁、5名50多岁、6名60多岁、11名70多岁、1名80多岁和2名90多岁。MB始终以左右对称的方式检测到。平均BVW为32 ± 初始（BVW1）上2.2 mm，32 ± 最后一次（BVW2）MRI检查2.4 mm。平均TVW为7.0 ± 初始值为2.3 mm（TVW1）和7.6 ± 最后一次（TVW2）MRI检查为2.7mm。此外，平均BMD为9.9 ± 初始值为1.3 mm（BMD1）和10 ± 最后一次（BMD2）MRI检查为1.3mm。从统计数据来看，没有任何年龄段的BVW1、BVW2、TVW1、TVW2、BMD1或BMD2具有较大的维度。TVW1和TVW2的变化在80多岁的患者中有显著差异；BMD1和BMD2之间的变化在任何年龄段或性别之间都没有差异。结论：单纯的衰老似乎不会促进MB萎缩。在健康的大脑中，MB可能是一生中固定的结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgical and Radiologic Anatomy ANATOMY & MORPHOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

CiteScore

2.70

自引率

14.30%

发文量

183

审稿时长

4-8 weeks

期刊介绍： Anatomy is a morphological science which cannot fail to interest the clinician. The practical application of anatomical research to clinical problems necessitates special adaptation and selectivity in choosing from numerous international works. Although there is a tendency to believe that meaningful advances in anatomy are unlikely, constant revision is necessary. Surgical and Radiologic Anatomy, the first international journal of Clinical anatomy has been created in this spirit. Its goal is to serve clinicians, regardless of speciality-physicians, surgeons, radiologists or other specialists-as an indispensable aid with which they can improve their knowledge of anatomy. Each issue includes: Original papers, review articles, articles on the anatomical bases of medical, surgical and radiological techniques, articles of normal radiologic anatomy, brief reviews of anatomical publications of clinical interest. Particular attention is given to high quality illustrations, which are indispensable for a better understanding of anatomical problems. Surgical and Radiologic Anatomy is a journal written by anatomists for clinicians with a special interest in anatomy.