The relationship between dietary inflammatory index and bone mineral density in CKD patients.

IF 1.5 4区 医学 Q3 HEMATOLOGY Therapeutic Apheresis and Dialysis Pub Date : 2024-02-01 Epub Date: 2023-09-10 DOI:10.1111/1744-9987.14063
Wenhui Wu, Xiurong Li, Jia Di, Hua Zhou, Hongyan Niu, Lu Chen, Qi Sha, Min Yang
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Abstract

Introduction: Chronic systemic inflammation was proposed as a critical factor in the development of osteoporosis. We aim to investigate the effect of the DII on bone mineral density (BMD) in CKD patients.

Methods: 2276 participants from NHANES were enrolled. The DII score was calculated based on a single 24-h dietary recall. Total BMD was measured using Dual-energy x-ray absorptiometry. A multiple-stepwise linear regression model was used to determine associations between BMD and DII in CKD patients.

Results: When DII >0.35, a negative correlation was obtained between DII and BMD (all β = -0.008 and p < 0.05). In subgroup analysis, BMD levels decreased across increasing tertiles of the DII for patients with non-osteoporosis, postmenopause, and low eGFR (p for trend ≤0.01).

Conclusion: Higher consumption of pro-inflammatory diet correlates negatively with the BMD levels in CKD patients.

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慢性肾脏病患者饮食炎症指数与骨矿物质密度之间的关系。
导言:慢性全身性炎症被认为是导致骨质疏松症的关键因素。我们旨在研究 DII 对慢性肾脏病患者骨矿物质密度 (BMD) 的影响。DII 评分根据单次 24 小时饮食回忆计算。采用双能 X 射线吸收测量法测量总 BMD。采用多元逐步线性回归模型确定慢性肾脏病患者的 BMD 与 DII 之间的关系:结果:当 DII >0.35 时,DII 与 BMD 之间呈负相关(均为 β = -0.008,p 结论:当 DII >0.35 时,DII 与 BMD 之间呈负相关(均为 β = -0.008,p 结论):摄入较多的促炎饮食与慢性肾脏病患者的 BMD 水平呈负相关。
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来源期刊
Therapeutic Apheresis and Dialysis
Therapeutic Apheresis and Dialysis 医学-泌尿学与肾脏学
CiteScore
3.00
自引率
10.50%
发文量
166
审稿时长
6-12 weeks
期刊介绍: Therapeutic Apheresis and Dialysis is the official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis and the Japanese Society for Dialysis Therapy. The Journal publishes original articles, editorial comments, review articles, case reports, meeting abstracts and Communications information on apheresis and dialysis technologies and treatments.
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