Evaluation and Comparison of Sensitivity and Specificity of Ultrasonography in Placenta Accreta Diagnosis in the Second and Third Trimesters.

Minoo Movahedi, Farinaz Farahbod, Mahsa Mootamedi
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Abstract

Background: Ultrasound is the selected technique for the detection of placenta accreta spectrum (PAS). This method can detect PAS in 80%-50% of cases. This study aimed to assess and compare the sensitivity and specificity of ultrasonography in the diagnosis of PAS after the first trimester.

Materials and methods: In this prospective study that was performed in 2020-2021 on 79 patients at high risk of PAS, all cases underwent ultrasonography in both 18-22 weeks of gestational age (GA) and 32-34 weeks of GA for evaluation of accreta. As per the risk factors, the delivery plan for all mothers was cesarean section. During the cesarean section, the placenta was examined for accreta, and if it was attached to the uterus, a diagnosis of placenta accreta was ascertained and a total abdominal hysterectomy was performed if the patient's bleeding was not controlled during the operation. The final diagnosis of PAS was made based on the pathology report.

Results: Ultrasound evaluation for PAS in 18-22 weeks of GA had 79.17% specificity, 51.61% sensitivity, 61.54% positive predictive value, and 71.70% negative predictive value. Ultrasound imaging for PAS in 32-34 weeks of GA had 60.8% specificity, 90% sensitivity, 62.52% positive predictive value, and 90.33% negative predictive value.

Conclusion: It should be concluded that PAS is a critical condition and if the patient is diagnosed in the second or third trimester, special strategies should be applied.

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超声诊断妊娠中晚期增生性胎盘的敏感性和特异性评价及比较。
背景:超声是检测胎盘增生谱(PAS)的首选技术。该方法检测PAS的检出率为80% ~ 50%。本研究旨在评估和比较超声检查在妊娠早期PAS诊断中的敏感性和特异性。材料与方法:本前瞻性研究于2020-2021年对79例PAS高危患者进行研究,所有病例均在孕龄18-22周和孕龄32-34周进行超声检查,以评估增生。根据风险因素,所有母亲的分娩计划都是剖宫产。剖宫产时检查胎盘是否增生,若胎盘附着于子宫,则诊断为胎盘增生,术中如出血未得到控制,则行全腹子宫切除术。PAS的最终诊断是根据病理报告。结果:超声评价GA 18-22周PAS的特异性为79.17%,敏感性为51.61%,阳性预测值为61.54%,阴性预测值为71.70%。GA 32 ~ 34周超声检查PAS特异性60.8%,敏感性90%,阳性预测值62.52%,阴性预测值90.33%。结论:PAS是一种危重症,如果患者在妊娠中期或晚期被诊断出来,应采取特殊的治疗策略。
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