Evaluation of Marketed Rosemary Essential Oils (Rosmarinus officinalis L.) in Terms of European Pharmacopoeia 10.0 Criteria.

IF 1.8 Q3 PHARMACOLOGY & PHARMACY Turkish Journal of Pharmaceutical Sciences Pub Date : 2023-08-22 DOI:10.4274/tjps.galenos.2022.78010
Timur Hakan Barak, Elif Bölükbaş, Hilal Bardakcı
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引用次数: 3

Abstract

Objectives: Various pure rosemary essential oil containing commercial products are in demand for their health-promoting and cosmetic claims in Türkiye. Although they are natural and harmless, they should be in compliance with European Pharmacopoeia (EP) criteria. Therefore, in this study, 15 rosemary oil samples sold in pharmacies, herbal shops, and online platforms in Türkiye were investigated in terms of "Rosemary Oil" EP 10.0. monograph criteria. In the current study, we aimed to evaluate the current quality status of rosemary essential oils in the Turkish market.

Materials and methods: Appearance, fatty oils and resinified essential oils, relative density, refractive index, optical rotation, and acid value tests were performed according to EP 10.0 and compared with the given standards. In addition, thin layer chromatography (TLC) and gas chromatography-mass spectrometry (GC-MS) analysis were conducted on all samples for advanced understanding of their phytochemical profile and harmony with EP standards.

Results: Fifteen pure rosemary oil-containing products from the Turkish market were evaluated. All of the samples were licensed as cosmetic products in Türkiye via the Ministry of Health. 83.1 to 96.9% of the ingredients of all samples were determined via GC-MS analysis. Results demonstrated that none of the samples from the Turkish rosemary essential oil market fully complied with the EP rosemary oil monograph standards.

Conclusion: Considering our data, it was revealed that enhanced regulations and auditing mechanisms are needed to improve the quality of products. When the difference between the sources of purchase is assessed, pharmacies are still better locations to obtain such products.

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根据欧洲药典10.0标准对市售迷迭香精油的评价。
目的:各种纯迷迭香精油含有商业产品的需求是他们的健康促进和化妆品声称在 rkiye。虽然它们是天然无害的,但它们应符合欧洲药典(EP)标准。因此,本研究以“迷迭香油”EP 10.0为标准,对我国药店、草药店、网络平台销售的15份迷迭香油样品进行了调查。论文的标准。在本研究中,我们旨在评估土耳其市场上迷迭香精油的质量现状。材料和方法:按照ep10.0进行外观、脂肪油和树脂化精油、相对密度、折射率、旋光度和酸值测试,并与给定标准进行比较。此外,对所有样品进行薄层色谱(TLC)和气相色谱-质谱(GC-MS)分析,以进一步了解其植物化学特征,并与EP标准保持一致。结果:对土耳其市场15种含迷迭香油的纯产品进行了评价。所有样品均经卫生部批准为日本化妆品,所有样品中83.1 ~ 96.9%的成分通过GC-MS分析。结果表明,土耳其迷迭香精油市场样品均不完全符合欧盟迷迭香精油专著标准。结论:结合我们的数据,需要加强监管和审计机制来提高产品质量。当评估采购来源之间的差异时,药店仍然是获得此类产品的较好地点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.60
自引率
5.90%
发文量
79
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