Hydrophobically Modified Abelmoschus esculentus Polysaccharide Based Nanoparticles and Applications: A Review.

Q3 Pharmacology, Toxicology and Pharmaceutics Current drug discovery technologies Pub Date : 2022-01-01 DOI:10.2174/1570163819666220801121857
Prashant Upadhyay, Shivani Agarwal, Sukirti Upadhyay
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引用次数: 1

Abstract

Nanomaterials are indeed a nanoscale technology that deals with the creation, evaluation, fabrication, and utilization of systems at the nanometre scale by manipulating their size and shape. We consider natural polysaccharides such as promising polysaccharides, which are biodegradable, nontoxic, abundant, and inexpensive bio-polymeric precursors for preparing the materials of choice in various industries. The aim is to review different methods to produce hydrophobically modified Abelmoschus esculentus nanoparticles and study the evaluation processes of these nanoparticles as given in the literature. It proved the benefits of derivatives of gum by introducing different chemical groups. The chemical functionalization of gum mainly includes the esterification, etherification, and crosslinking reactions of the hydroxyl groups and contains a special fibre which takes sugar levels in the blood under control, providing a sugar quantity suitable for the bowels. Okra contains mucilage that helps remove poisonous chemicals and bad cholesterol, often overloads the liver. Recovering from psychological conditions, like depression, general weakness, and joint healthiness can be done with Okra. Someone additionally applied it for pulmonary inflammation, bowel irritation, and sore throat. Purgative properties okra possesses are beneficial for bowel purification. It is used to counteract the acids. Fibre okra contains a valuable nutrient for intestinal microorganisms and ensures proper intestine functionality. It also protects the mucosa of the digestive tract by covering them with an extra layer because of its alkaline nature. Nanotechnology has emerged as a critical component of pharmaceutics, with many applications in drug carriers of interest aimed at improving drug clinical outcomes such as cancer, diabetes mellitus, wound care management, atopic dermatitis, cosmeceutical, etc. Beneficial outcomes of this review are discussed briefly.

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疏水修饰木耳多糖纳米颗粒及其应用研究进展
纳米材料确实是一种纳米级技术,通过控制其尺寸和形状来处理纳米级系统的创建、评估、制造和利用。我们考虑天然多糖,如有前途的多糖,它们是可生物降解的,无毒的,丰富的,廉价的生物聚合物前体,用于制备各种工业选择的材料。目的是回顾不同的方法来生产疏水修饰的竹沙鼠纳米颗粒,并研究这些纳米颗粒的评价过程中给出的文献。它通过引入不同的化学基团证明了口香糖衍生物的好处。口香糖的化学功能化主要包括羟基的酯化、醚化和交联反应,并含有一种特殊的纤维,可以控制血液中的糖水平,提供适合肠道的糖量。秋葵含有粘液,有助于清除有毒化学物质和有害胆固醇,通常会使肝脏负担过重。从抑郁、全身虚弱和关节健康等心理状况中恢复过来可以用秋葵。有人还用它来治疗肺部炎症、肠道刺激和喉咙痛。秋葵具有净化肠道的功效。它是用来中和酸的。秋葵纤维含有对肠道微生物有价值的营养物质,确保肠道正常运作。由于它的碱性,它还通过覆盖一层额外的粘膜来保护消化道黏膜。纳米技术已成为药剂学的重要组成部分,在药物载体中有许多应用,旨在改善药物临床结果,如癌症、糖尿病、伤口护理管理、特应性皮炎、药妆等。简要讨论了本综述的有益结果。
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来源期刊
Current drug discovery technologies
Current drug discovery technologies Pharmacology, Toxicology and Pharmaceutics-Drug Discovery
CiteScore
3.70
自引率
0.00%
发文量
48
期刊介绍: Due to the plethora of new approaches being used in modern drug discovery by the pharmaceutical industry, Current Drug Discovery Technologies has been established to provide comprehensive overviews of all the major modern techniques and technologies used in drug design and discovery. The journal is the forum for publishing both original research papers and reviews describing novel approaches and cutting edge technologies used in all stages of drug discovery. The journal addresses the multidimensional challenges of drug discovery science including integration issues of the drug discovery process.
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