Harnessing the Therapeutic Potential of Dillenia indica: An Overview of Recent Dosage Form Developments.

Q3 Pharmacology, Toxicology and Pharmaceutics Current drug discovery technologies Pub Date : 2024-04-17 DOI:10.2174/0115701638292980240407135246
Aditya Bora, Pallab Kalita, Parimita Kalita, Rudra Pasad Adhikari, Aaditya Das, Rizuwan Zaheer, Mustaf Alam Laskar, K. Pathak
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Abstract

Dillenia indica, commonly known as Elephant Apple, is a significant medicinal plant found in Assam, North-East India. This evergreen shrub or small to medium-sized tree possesses not only tasty components but also a plethora of beneficial therapeutic characteristics. This review article aims to explore the potential use of Dillenia indica in the treatment of diabetes and other diseases, as well as discuss various patents associated with this plant. The study focuses on identifying different formulations derived from various parts of Dillenia indica. These formulations encompass a range of dosage forms, including mucoadhesive buccal dosage forms, buccal patches, microbeads, emulgel, and mucoadhesive nasal gel. Each of these dosage forms offers unique advantages and applications. Mucoadhesive buccal dosage forms are designed to adhere to the oral mucosa, allowing for controlled drug release and enhanced absorption. Buccal patches provide a convenient and localized delivery system for specific therapeutic agents. Microbeads offer a versatile approach for encapsulating drugs and facilitating their controlled release. Emulgels combine the benefits of both emulsions and gels, providing improved drug delivery and stability. Mucoadhesive nasal gels offer a non-invasive route for drug administration, allowing for rapid absorption through the nasal mucosa. By exploring these different formulations, researchers aim to harness the therapeutic potential of Dillenia indica in a variety of diseases, including diabetes. The study also highlights the importance of patents associated with Dillenia indica, indicating the growing interest in its medicinal properties and potential commercial applications. Dillenia indica holds promise as a valuable medicinal plant, with its diverse therapeutic characteristics and tasty components. The study discussed various formulations derived from different parts of the plant, showcasing their potential applications in the treatment of diseases. Further research and development in this field may lead to the discovery of novel treatments and contribute to the advancement of pharmaceutical science.
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利用莳萝的治疗潜力:最新剂型发展综述。
Dillenia indica 俗称 "象苹果",是印度东北部阿萨姆邦的一种重要药用植物。这种常绿灌木或中小型乔木不仅味道鲜美,还具有大量有益的治疗特性。这篇综述文章旨在探讨 Dillenia indica 在治疗糖尿病和其他疾病方面的潜在用途,并讨论与这种植物相关的各种专利。研究重点是确定从籼米草不同部位提取的不同配方。这些制剂包括一系列剂型,包括粘液黏附口腔剂型、口腔贴片、微珠、乳胶和粘液黏附鼻凝胶。每种剂型都具有独特的优势和应用。粘液粘附性口腔剂型可粘附在口腔粘膜上,从而控制药物释放并促进吸收。颊贴为特定治疗药物提供了一种方便的局部给药系统。微珠是一种封装药物并促进药物控释的多功能方法。凝胶剂结合了乳剂和凝胶剂的优点,可提高给药效果和稳定性。黏附性鼻凝胶提供了一种非侵入性给药途径,可通过鼻黏膜快速吸收药物。通过探索这些不同的配方,研究人员旨在利用籼米藻在包括糖尿病在内的多种疾病中的治疗潜力。这项研究还强调了与莳萝有关的专利的重要性,表明人们对其药用特性和潜在商业应用的兴趣与日俱增。莳萝具有多种治疗特性和美味成分,有望成为一种有价值的药用植物。研究讨论了从该植物不同部位提取的各种配方,展示了它们在治疗疾病方面的潜在应用。在这一领域的进一步研究和开发可能会发现新的治疗方法,并促进医药科学的进步。
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来源期刊
Current drug discovery technologies
Current drug discovery technologies Pharmacology, Toxicology and Pharmaceutics-Drug Discovery
CiteScore
3.70
自引率
0.00%
发文量
48
期刊介绍: Due to the plethora of new approaches being used in modern drug discovery by the pharmaceutical industry, Current Drug Discovery Technologies has been established to provide comprehensive overviews of all the major modern techniques and technologies used in drug design and discovery. The journal is the forum for publishing both original research papers and reviews describing novel approaches and cutting edge technologies used in all stages of drug discovery. The journal addresses the multidimensional challenges of drug discovery science including integration issues of the drug discovery process.
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