Prevalence of microbial nosocomial infections in the resuscitation unit of the University Hospital of Annaba-Algeria

IF 0.4 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY Annales de biologie clinique Pub Date : 2022-11-01 DOI:10.1684/abc.2022.1766
Chahrazed Benzaid, Lazhari Tichati, Mahmoud Rouabhia, Sonia Akil Dahdouh
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Abstract

Nosocomial infections constitute a significant public health problem but are poorly controlled in our health structures, especially those associated with resuscitation care. The first objective of this study was to identify the different microbial strains present in different biological samples taken from patients staying in the resuscitation unit of the Annaba University Hospital Center. The second objective was to assess the antimicrobial sensitivity of isolated microbes from the patients’ samples, to determine the risk factors, the most incriminated microbial agents in nosocomial infections. During the study period from January 2013 to December 2016, we collected 1,151 biological samples from 1,938 patients admitted to Resuscitation Medical Service. The samples were subjected to different microbiological analyses. Our results showed that over 59% of the collected samples were microbiologically positive. The identified species include Candida albicans (115 cases) and Candida.sp (81 cases). The Gram-negative bacterial strains found in the samples included Acinetobacter baumannii (108 cases), Klebssiella pneumoniae (99 cases) Pseudomonas aeruginosa (79 cases), and Escherichia coli (73 cases). Gram positive bacteria included Staphylococcus aureus (94 cases) and Enterococcus faecalis (53 cases). The antibiogram analyses showed significant antibiotic resistance reaching 93.75% for ampicillin, but sensitivity to colistin reaching 81.81%. Moreover, the fungal strains are represented by the genus albicans, showing a significant resistance to antifungals, reaching 80% with miconazole. Conclusion. The nosocomial infections in the medical unit were caused by the candida genus and multi-resistant bacteria to various antibiotics and antifungals. The most important factor associated with these infections was the use of medical devices.

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阿尔及利亚安纳巴大学医院复苏病房微生物医院感染的流行情况
医院感染是一个重大的公共卫生问题,但在我们的卫生机构中控制不力,特别是与复苏护理有关的感染。本研究的第一个目的是鉴定来自安纳巴大学医院中心复苏病房的患者的不同生物样本中存在的不同微生物菌株。第二个目的是评估从患者样本中分离出的微生物的抗菌药物敏感性,以确定院内感染的危险因素和最相关的微生物因子。在2013年1月至2016年12月的研究期间,我们从复苏医疗服务部收治的1938例患者中收集了1151份生物样本。对这些样品进行了不同的微生物分析。我们的结果显示,超过59%的采集样本微生物阳性。鉴定的菌种包括白色念珠菌(115例)和念珠菌。Sp(81例)检出革兰氏阴性菌株包括鲍曼不动杆菌(108例)、肺炎克雷伯菌(99例)、铜绿假单胞菌(79例)和大肠杆菌(73例)。革兰氏阳性菌包括金黄色葡萄球菌94例,粪肠球菌53例。抗菌谱分析显示,对氨苄西林的耐药性为93.75%,对粘菌素的敏感性为81.81%。此外,真菌菌株以白色念珠菌属为代表,对抗真菌药物表现出显著的耐药性,对咪康唑的耐药性达到80%。结论。该医疗单位院内感染主要由念珠菌属和多种抗生素及抗真菌药多重耐药菌引起。与这些感染相关的最重要因素是医疗器械的使用。
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来源期刊
Annales de biologie clinique
Annales de biologie clinique 医学-医学:研究与实验
CiteScore
0.80
自引率
20.00%
发文量
53
审稿时长
6-12 weeks
期刊介绍: Multidisciplinary information with direct relevance to everyday practice Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation. With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.
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