L. S. Dolci, M. Mirasoli, Angela Buragina, M. Guardigli, A. Roda, F. Bonvicini, Francesca Di Furio
{"title":"Point-of-care Parvovirus B19 detection and genotyping based on microfluidics and chemiluminescence “contact” imaging detection","authors":"L. S. Dolci, M. Mirasoli, Angela Buragina, M. Guardigli, A. Roda, F. Bonvicini, Francesca Di Furio","doi":"10.1109/IWBP.2011.5954864","DOIUrl":null,"url":null,"abstract":"A diagnostic device suitable for Parvovirus B19 genotyping and quantitative DNA detection was developed, based on hybridization with immobilized oligonucleotide probes and chemiluminescence detection. The microfluidic chamber was directly coupled with a CCD sensor in a “contact” imaging configuration to obtain a portable device suitable for point-of-care applications.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"27 6","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2011 International Workshop on Biophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IWBP.2011.5954864","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A diagnostic device suitable for Parvovirus B19 genotyping and quantitative DNA detection was developed, based on hybridization with immobilized oligonucleotide probes and chemiluminescence detection. The microfluidic chamber was directly coupled with a CCD sensor in a “contact” imaging configuration to obtain a portable device suitable for point-of-care applications.