The phenomenon of laser-induced photodissosiation of hemoglobin complexes in cutaneous blood vessels and its biomedical application

M. Asimov
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引用次数: 2

Abstract

New laser-optical technology based on photodissosiation of oxyhemoglobin and carboxyhemoglobin in vivo for local tissue oxygenation and increasing the efficiency of elimination of carbon monoxide poisoning effect is proposed. The results of both numerical simulations of “laser-tissue” interaction in terms of maximal effect on blood oxyhemoglobin and carboxyhemoglobin in cutaneous blood vessels and experimental investigations the efficiency of their photodissosiation are presented. It is shown that despite of similarity and overlapping of carboxyhemoglobin and oxyhemoglobin action spectrum significant difference on quantum yields of photodissociation makes possible to develop a novel optical method of elimination of carbon monoxide poisoning effect.
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激光诱导皮肤血管中血红蛋白复合物的光分解现象及其生物医学应用
提出了一种基于氧合血红蛋白和碳合血红蛋白在体内光分解的激光光学新技术,用于局部组织氧合,提高一氧化碳中毒效应的消除效率。本文介绍了激光-组织相互作用对皮肤血管中血氧血红蛋白和碳氧血红蛋白最大影响的数值模拟结果和对其光分解效率的实验研究。结果表明,尽管氧合血红蛋白和羧化血红蛋白的作用谱具有相似性和重叠性,但光解量子产率的显著差异使得开发一种消除一氧化碳中毒效应的新型光学方法成为可能。
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