Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Maxwell Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, L. Wang, S. Hsu
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引用次数: 5
Abstract
Yang et al. unravel the molecular mechanism by which the tumor suppressor BAP1 is shuttled into the nucleus by TNPO1. TNPO1 sterically competes with UBE2O for monoubiquitination sites within the nuclear localization sequence of BAP1 to prevent its cytoplasmic retention.
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